{"id":"W2979656022","doi":"10.1016/j.cjca.2019.07.520","title":"LOSS OF ENDOTHELIAL CELL-SPECIFIC AUTOPHAGY-RELATED PROTEIN 7 EXACERBATES DOXORUBICIN-INDUCED CARDIOTOXICITY","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Public Health","funders":"","keywords":"Cardiotoxicity; Autophagy; Medicine; Doxorubicin; Apoptosis; Cardioprotection; Heart failure; Anthracycline; Pharmacology; Cardiomyopathy; Internal medicine; Endothelial dysfunction; Chemotherapy; Endocrinology; Ischemia; Cancer; Breast cancer; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636378,0.0002503254,0.0003771995,0.0001645873,0.0001843464,0.0002391641,0.0001500346,0.0002943315,0.001837229],"category_scores_gemma":[0.0001463911,0.0001339304,0.000246503,0.00008528483,0.0002630416,0.0001901354,0.0001673659,0.0008783939,0.0002362953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003206206,"about_ca_system_score_gemma":0.0004320236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008697494,"about_ca_topic_score_gemma":0.003073921,"domain_scores_codex":[0.999836,0.00002728211,0.00001191678,0.00002248883,0.00003768642,0.00006461473],"domain_scores_gemma":[0.9999157,0.000009172201,0.00002547928,0.000007363649,0.00001000121,0.00003224086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001570879,0.0003611259,0.001093022,0.00009085247,0.00003133074,0.0001614513,0.00002702071,0.0001887106,0.9918045,0.0002224709,0.0004101596,0.004038608],"study_design_scores_gemma":[0.0004093787,0.01044792,0.05395487,0.00006570961,0.0002388759,0.001186628,0.0003696312,0.005807567,0.9196219,0.0003286575,0.007535075,0.00003377899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957237,0.001437622,0.0009029761,0.0002822243,0.0001207994,0.00003208176,0.0001625938,0.00005751012,0.001280454],"genre_scores_gemma":[0.9975024,0.0006044001,0.00037939,0.00007651208,0.00001225799,0.00002019888,0.0001529259,0.00000582511,0.001246084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001837229,"threshold_uncertainty_score":0.006146133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01152818434601407,"score_gpt":0.2194123722269645,"score_spread":0.2078841878809504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}