{"id":"W2979670769","doi":"10.1182/blood.v128.22.371.371","title":"Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells Via Transcription Factor Conversion of Hemogenic Endothelium","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Biology; Stem cell; Cell biology; Haematopoiesis; RUNX1; Immunology; Progenitor cell; Cellular differentiation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001848306,0.0002159881,0.0001149732,0.0002166054,0.00008720661,0.0002353873,0.0001319723,0.0001206549,0.001626143],"category_scores_gemma":[0.0001215327,0.0001147652,0.0001853077,0.0001336151,0.0001334187,0.0000700509,0.0001902143,0.0003785091,0.0006340227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008872867,"about_ca_system_score_gemma":0.0001367297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002327101,"about_ca_topic_score_gemma":0.0003543448,"domain_scores_codex":[0.9998994,0.00001161076,0.00001267218,0.00001940812,0.00004044105,0.00001653855],"domain_scores_gemma":[0.9999292,0.00001588673,0.00001692169,0.00001390707,0.000008872538,0.00001532152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003320943,0.00001405969,0.0003046078,0.00002510219,0.000003347042,0.00006417673,0.00001240407,0.0001302865,0.9956205,0.0002374479,0.0000704324,0.003484408],"study_design_scores_gemma":[0.0000136641,0.0001343762,0.003213396,0.000009233205,0.00001620891,0.0003004483,0.00001058606,0.0009687622,0.9900558,0.00009026275,0.00518455,0.00000280043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9617138,0.001117242,0.02869365,0.0001045439,0.00003887201,0.0002776422,0.001640416,0.0004017315,0.006012115],"genre_scores_gemma":[0.9815983,0.0005780759,0.009750447,0.0000608054,0.000009522467,0.0001006718,0.002771229,0.00003037614,0.005100647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001626143,"threshold_uncertainty_score":0.005439937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01331571882822824,"score_gpt":0.2208997723034673,"score_spread":0.207584053475239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}