{"id":"W2979673013","doi":"10.14309/01.ajg.0000592760.20054.85","title":"806 Long-Term Safety and Efficacy of Risankizumab Treatment in Patients With Crohn’s Disease: 3-Year Interim Results From the Ongoing Phase 2 Open-Label Extension Study","year":2019,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Internal medicine; Adverse effect; Open label; Bristol-Myers; Open label study; Interim analysis; Maintenance therapy; Crohn's disease; Clinical trial; Interim; Gastroenterology; Surgery; Disease; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006003314,0.0009758204,0.002159917,0.000350085,0.0005805735,0.001135178,0.0005306843,0.001214902,0.002645689],"category_scores_gemma":[0.001976292,0.0004447279,0.002041155,0.000317504,0.0006027648,0.001063115,0.0004341255,0.003168591,0.001018337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004700417,"about_ca_system_score_gemma":0.001183586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003115786,"about_ca_topic_score_gemma":0.0005853337,"domain_scores_codex":[0.9985893,0.0006586454,0.0001303621,0.0001411983,0.0002200548,0.0002602829],"domain_scores_gemma":[0.9975389,0.0005373502,0.0006590031,0.000321901,0.0002660507,0.0006768058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8094964,0.04586894,0.02707957,0.000581527,0.001614441,0.0002850159,0.0003383462,0.001296894,0.02736473,0.00009176898,0.003817442,0.08216495],"study_design_scores_gemma":[0.2041568,0.7069143,0.07603294,0.00005711873,0.001137539,0.0003396555,0.0000750405,0.0008089553,0.006605946,0.0001590197,0.003658635,0.00005398309],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920028,0.002094327,0.0006065914,0.0002899246,0.0000815051,0.001108434,0.002207166,0.00007076695,0.001538535],"genre_scores_gemma":[0.9882036,0.0007805282,0.001566313,0.0006736543,0.000223716,0.001444787,0.005411098,0.00002325811,0.001673167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006003314,"threshold_uncertainty_score":0.03174895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01055771085369417,"score_gpt":0.2785333631030842,"score_spread":0.26797565224939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}