{"id":"W2979675032","doi":"10.1182/blood.v116.21.2005.2005","title":"Concurrent BCL2 and MYC Protein Expression by Immunohistochemistry Determines Clinical Outcome In DLBCL Patients Treated with R-CHOP","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Immunohistochemistry; Diffuse large B-cell lymphoma; Germinal center; Fluorescence in situ hybridization; Vincristine; clone (Java method); Lymphoma; CHOP; Immunophenotyping; Pathology; Biology; Medicine; Cancer research; Internal medicine; Molecular biology; Antibody; Cyclophosphamide; Immunology; B cell; Flow cytometry; Gene; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002014406,0.0001398131,0.0001884078,0.0005201044,0.0001746224,0.0003221535,0.00014479,0.0002450055,0.001270918],"category_scores_gemma":[0.00064932,0.0001048877,0.000113321,0.0003338979,0.0002021763,0.0001767013,0.0001891903,0.0002240916,0.0002473953],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001859701,"about_ca_system_score_gemma":0.0000785638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005496636,"about_ca_topic_score_gemma":0.000814135,"domain_scores_codex":[0.9998705,0.0000288261,0.00001530064,0.00002980008,0.000028036,0.00002759855],"domain_scores_gemma":[0.9996743,0.00009265458,0.00009912204,0.00001249244,0.00003990656,0.00008148216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005530203,0.00003506298,0.987238,0.00001043141,0.00002465373,0.000392578,0.00005369485,0.00006370076,0.008625517,0.00000573613,0.00006912601,0.002928493],"study_design_scores_gemma":[0.00002407288,0.0002474784,0.9952512,0.000003618186,0.0000338303,0.002432671,0.0001204369,0.000313602,0.001361872,0.00001747589,0.0001913941,0.000002395335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995503,0.0001521173,0.00005589062,0.00001089594,0.000001092094,0.000002449938,0.00003384917,0.000002585389,0.0001908713],"genre_scores_gemma":[0.9997805,0.00003567146,0.00004458613,0.000008928119,0.000002087663,0.000002133845,0.00007573579,8.805259e-7,0.00004928495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001270918,"threshold_uncertainty_score":0.004251659,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01285526685516439,"score_gpt":0.3025816071338898,"score_spread":0.2897263402787253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}