{"id":"W2979703119","doi":"10.1371/journal.pgen.1008412","title":"Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing","year":2019,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Fonds de Recherche du Québec - Santé; National Institute of General Medical Sciences; Directorate for Biological Sciences; Agence Nationale de la Recherche; Fondation Bettencourt Schueller; Centre National de la Recherche Scientifique; Fondation pour la Recherche Médicale; National Institute of Environmental Health Sciences; Institut National de la Santé et de la Recherche Médicale; Fonds de Recherche du Québec-Société et Culture; National Science Foundation","keywords":"Synapsis; Meiosis; Homologous chromosome; Biology; Centromere; Genetics; Chromosomal crossover; Synaptonemal complex; Chromosome segregation; Bivalent (engine); Pairing; Chromosome; Gene; Chemistry; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001324208,0.0002149759,0.0001723811,0.0002389517,0.0002037653,0.0003268331,0.0002756166,0.000239902,0.001022424],"category_scores_gemma":[0.0001283028,0.0001888023,0.0001349514,0.00009575097,0.0002219194,0.000143689,0.0003748576,0.000299211,0.0003805521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004464815,"about_ca_system_score_gemma":0.00026395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009026233,"about_ca_topic_score_gemma":0.002402761,"domain_scores_codex":[0.9998858,0.000009987243,0.000006622345,0.0000260882,0.0000399126,0.00003152217],"domain_scores_gemma":[0.9998616,0.00001216303,0.00003934551,0.00001684035,0.00001379718,0.00005623185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003015234,0.00000518089,0.0004031141,0.00001165101,0.000002153139,0.0000274295,0.000007898648,0.00004409472,0.9987405,0.0001746167,0.00001219809,0.0005410837],"study_design_scores_gemma":[0.000005402331,0.00006256672,0.01472837,0.000004310072,0.000005379643,0.0001314482,0.00002281466,0.00112908,0.9822582,0.00007757587,0.001571517,0.000003294839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997315,0.0003915123,0.001066377,0.00002653812,0.00000572953,0.000003448842,0.0000513864,0.00004920797,0.001090834],"genre_scores_gemma":[0.9982242,0.00008379883,0.0004503375,0.000006202297,0.000001653131,0.000002373559,0.00006656807,0.000009661284,0.001155194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001022424,"threshold_uncertainty_score":0.003420353,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009033265404438226,"score_gpt":0.2072336961619567,"score_spread":0.1982004307575184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}