{"id":"W2979818193","doi":"10.14309/01.ajg.0000592880.13323.ac","title":"836 Tofacitinib Efficacy in Patients With Moderate to Severe Ulcerative Colitis: Subgroup Analyses of OCTAVE Induction 1 & 2 and OCTAVE Sustain by 5-Aminosalicylates Use","year":2019,"lang":"en","type":"article","venue":"The American Journal of Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Tofacitinib; Medicine; Octave (electronics); Concomitant; Internal medicine; Placebo; Ulcerative colitis; Randomized controlled trial; Gastroenterology; Surgery; Rheumatoid arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003356465,0.0009987626,0.002982408,0.0009623335,0.0002749659,0.0009578847,0.0005677298,0.0008938676,0.003372363],"category_scores_gemma":[0.003903987,0.0003072605,0.009255858,0.001058514,0.0002756124,0.0006430259,0.0006804123,0.0009417577,0.0003296454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003723907,"about_ca_system_score_gemma":0.0006520256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001158834,"about_ca_topic_score_gemma":0.00261889,"domain_scores_codex":[0.9968458,0.001165277,0.0006098208,0.0006071242,0.0004408027,0.0003311758],"domain_scores_gemma":[0.9982831,0.0008677812,0.0003611073,0.0002442051,0.00009805591,0.0001457191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2762215,0.0007704477,0.5359341,0.004023465,0.114432,0.0009207137,0.0005147442,0.003052915,0.008129673,0.0005222594,0.005270636,0.05020754],"study_design_scores_gemma":[0.01756609,0.02019464,0.8799124,0.0004343361,0.06026684,0.001103067,0.0007426307,0.007778414,0.001760169,0.001477012,0.008613911,0.0001504521],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814221,0.009654148,0.0009855492,0.0002877314,0.0001668498,0.0004988751,0.004981543,0.00003846259,0.001964865],"genre_scores_gemma":[0.9963009,0.00053686,0.0003487439,0.0001462038,0.0000987705,0.0003772477,0.00167854,0.00001521894,0.0004974319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003372363,"threshold_uncertainty_score":0.01775092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008584901829646455,"score_gpt":0.251262789917471,"score_spread":0.2426778880878246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}