{"id":"W2979822567","doi":"10.1182/blood.v116.21.1165.1165","title":"TINF2 Mutations In Patients with Aplastic Anemia Result In Low TIN2 Expression In Hematopoietic Cells and Very Short Telomeres.","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Dyskeratosis congenita; Telomere; Aplastic anemia; Biology; Shelterin; Telomerase; Exon; Cancer research; Genetics; Molecular biology; Gene; Immunology; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001486114,0.0005603,0.0002630938,0.0009439016,0.0004700363,0.0002902596,0.0002478087,0.0005289463,0.002410675],"category_scores_gemma":[0.0008952765,0.0002178487,0.0002079664,0.0005087572,0.0003428915,0.0001502166,0.0001818223,0.0002684145,0.0002580236],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002433806,"about_ca_system_score_gemma":0.0001033584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001692347,"about_ca_topic_score_gemma":0.001726822,"domain_scores_codex":[0.9998218,0.0000266796,0.00002045385,0.00005805992,0.00003689528,0.00003600903],"domain_scores_gemma":[0.9996908,0.00009793614,0.00007750734,0.00001442021,0.00002963218,0.00008974493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006843277,0.0001079606,0.9556702,0.00003951466,0.00006388692,0.01312387,0.0004041534,0.0001034516,0.02576942,0.00007170797,0.0003174318,0.003644197],"study_design_scores_gemma":[0.00006510189,0.000447106,0.9620272,0.00001503115,0.00006882073,0.03157335,0.0002477817,0.0004631717,0.00416728,0.00006425623,0.0008505763,0.00001020768],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991653,0.0001301856,0.00009689108,0.00001914151,0.000005335209,0.000007092385,0.0001166731,0.000007966824,0.0004513976],"genre_scores_gemma":[0.9995554,0.00002788679,0.00008164856,0.00002262864,0.000004090241,0.000003639158,0.0001069879,0.000002200371,0.0001955616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002410675,"threshold_uncertainty_score":0.008064508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004868574062163351,"score_gpt":0.2121368278310622,"score_spread":0.2072682537688989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}