{"id":"W2979850125","doi":"10.1182/blood.v120.21.3729.3729","title":"Chronic Myeloid Leukemia Patients Undergoing Interferon Alpha Therapy Exhibit Normal Peripheral Blood Gamma Delta T Cells That May Be Expanded in Vitro to Generate Predominantly CD45RA-Positive Effector Memory Cells for Immunotherapy","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Immunology; Immunotherapy; NKG2D; K562 cells; Peripheral blood mononuclear cell; Medicine; Immunophenotyping; Cytotoxic T cell; Interferon gamma; Leukemia; Myeloid leukemia; Immune system; Biology; In vitro; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000995102,0.0001607434,0.0002228445,0.0001920154,0.0001327972,0.0002053491,0.00005709006,0.0001598145,0.00203237],"category_scores_gemma":[0.0002539113,0.0000782127,0.00006642983,0.0001154722,0.0001178827,0.000103348,0.00009020545,0.0002039564,0.0004108632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009841122,"about_ca_system_score_gemma":0.00006528627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003013165,"about_ca_topic_score_gemma":0.0003652951,"domain_scores_codex":[0.9999224,0.00001331228,0.00001082194,0.00001801753,0.0000147696,0.00002063188],"domain_scores_gemma":[0.9998633,0.00003602787,0.00003211709,0.00001858454,0.00001440497,0.00003561522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00277413,0.0002517432,0.1616431,0.00005555337,0.00003189257,0.001705679,0.0004008989,0.0001455943,0.8075356,0.0001098069,0.0002394221,0.02510657],"study_design_scores_gemma":[0.0001232071,0.003226196,0.917199,0.00002018343,0.00004962873,0.007967344,0.0002428344,0.0007200759,0.06749721,0.0001299836,0.002812984,0.00001143086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987677,0.0001447852,0.0001401777,0.00000902273,0.000003258508,0.00001037845,0.00006241205,0.000007323991,0.0008548534],"genre_scores_gemma":[0.998892,0.0000792689,0.0001641484,0.00003020095,0.000007145326,0.00001675904,0.0002065341,0.000003262107,0.0006007841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00203237,"threshold_uncertainty_score":0.006798983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01823710701992393,"score_gpt":0.2708920577257191,"score_spread":0.2526549507057951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}