{"id":"W2979857835","doi":"10.1182/blood.v118.21.4509.4509","title":"Pharmacokinetics and Safety of a Novel Conditioning Regimen, Individualized Once-Daily Intravenous Busulfan with Bortezomib, in Relapsed Multiple Myeloma Patients Undergoing a Second Autologous Hematopoietic Stem Cell Transplantation","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Medicine; Busulfan; Melphalan; Multiple myeloma; Bortezomib; Mucositis; Hematopoietic stem cell transplantation; Regimen; Internal medicine; Transplantation; Oncology; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000365428,0.0002131038,0.0004787383,0.0002081844,0.0001678868,0.0005891336,0.00015281,0.0003009768,0.000807502],"category_scores_gemma":[0.001109016,0.0001597592,0.0003183071,0.0002793374,0.0002144446,0.0003243051,0.0001745457,0.0007979855,0.0002115505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005565144,"about_ca_system_score_gemma":0.0004695788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000724283,"about_ca_topic_score_gemma":0.0006210477,"domain_scores_codex":[0.9997405,0.00006827449,0.00001510528,0.0000683176,0.00007716213,0.00003063089],"domain_scores_gemma":[0.999569,0.00007723406,0.0001776623,0.00003581572,0.00003188154,0.0001083407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.09970748,0.00425405,0.2971151,0.0005142165,0.001261152,0.000993315,0.0008099129,0.00856481,0.3219747,0.0005833781,0.003207763,0.261014],"study_design_scores_gemma":[0.003569536,0.08023153,0.8106013,0.0001007559,0.001667027,0.004115968,0.0003240811,0.02396091,0.06226933,0.0005318758,0.01251075,0.0001168905],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997617,0.001470816,0.0003688359,0.00007304786,0.00002032953,0.00001999699,0.0001045299,0.00002698202,0.000298468],"genre_scores_gemma":[0.9989387,0.0002685023,0.0003503526,0.00007909749,0.00002601906,0.00001363182,0.0001555089,0.000008788794,0.0001594479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000807502,"threshold_uncertainty_score":0.004037797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110035861322016,"score_gpt":0.2483175071849736,"score_spread":0.2272171485717534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}