{"id":"W2979861852","doi":"10.1182/blood.v120.21.1753.1753","title":"Niche Requirements of Transient Leukemia Cells in Down Syndrome","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Haematopoiesis; GATA1; Bone marrow; Biology; Leukemia; Context (archaeology); Fetus; Trisomy; Stem cell; Immunology; Pathology; Cancer research; Medicine; Cell biology; Genetics; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007576642,0.0001577314,0.0001545481,0.0002424748,0.000109334,0.0002517932,0.0001268427,0.0001685082,0.001388173],"category_scores_gemma":[0.000111525,0.00009118715,0.0001009776,0.0001305313,0.0001453331,0.0001148665,0.000283771,0.0002376489,0.0003105246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002102091,"about_ca_system_score_gemma":0.0001263434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000669368,"about_ca_topic_score_gemma":0.001169897,"domain_scores_codex":[0.9999123,0.00001246365,0.000008840605,0.00001755013,0.00002537539,0.00002345164],"domain_scores_gemma":[0.9998953,0.00002966738,0.00002430858,0.000007269472,0.00001001045,0.00003334238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009874262,0.000006873852,0.001645058,0.00002703033,0.000001389767,0.0002149624,0.00002828541,0.00003203189,0.9968399,0.0001014477,0.00002565644,0.000978636],"study_design_scores_gemma":[0.00004943111,0.0007407157,0.1189451,0.00002683548,0.00002875783,0.005115493,0.0004564542,0.001741706,0.8630276,0.0002007732,0.009655601,0.0000115761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974267,0.0009930274,0.0006009199,0.0000235627,0.000005291977,0.000007182669,0.0002926231,0.0000161922,0.0006344919],"genre_scores_gemma":[0.9977724,0.0003823932,0.0006047156,0.0000207218,0.000004510642,0.00001236625,0.0005015867,0.000005687029,0.0006956368],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001388173,"threshold_uncertainty_score":0.004643857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02832398170489233,"score_gpt":0.2941409615994923,"score_spread":0.2658169798946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}