{"id":"W2979863015","doi":"10.1182/blood.v116.21.22.22","title":"Mouse Models of the Common, Recurring Type 1 von Willebrand Disease Mutations Y1584C and R1205H","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Von Willebrand disease; ADAMTS13; Von Willebrand factor; Platelet; Knockout mouse; Wild type; Chemistry; Missense mutation; Molecular biology; Bleeding time; Internal medicine; Endocrinology; Mutant; Mutation; Medicine; Biology; Gene; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006231804,0.001510608,0.0006589317,0.001898676,0.0005069869,0.0006029207,0.001062998,0.00205927,0.004619588],"category_scores_gemma":[0.0001909608,0.0005639811,0.0009206078,0.0005839977,0.0006732928,0.0005059321,0.0004281027,0.002050018,0.001652869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006864592,"about_ca_system_score_gemma":0.0003425482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006934938,"about_ca_topic_score_gemma":0.0007771575,"domain_scores_codex":[0.9992713,0.0001049831,0.0001182585,0.0001946491,0.0001795452,0.0001312236],"domain_scores_gemma":[0.9995075,0.00006493933,0.0002005403,0.00004964307,0.00003868592,0.0001386081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000653522,0.00058745,0.0002996828,0.0001083878,0.00003345884,0.0004439267,0.00006607328,0.0001922148,0.9950336,0.000755681,0.0003271475,0.001498683],"study_design_scores_gemma":[0.0006342348,0.00582648,0.004225635,0.00007795223,0.0002218282,0.003762953,0.0001197008,0.001898386,0.9694008,0.0004809593,0.01331012,0.000040894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9768984,0.002346134,0.01074309,0.0005762419,0.0003135201,0.0005683283,0.004123802,0.0006317828,0.003798629],"genre_scores_gemma":[0.9370292,0.004339712,0.02005306,0.0003779217,0.0001199162,0.001592529,0.006156725,0.0003101433,0.03002076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004619588,"threshold_uncertainty_score":0.01545411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01153480312925542,"score_gpt":0.2443970019718597,"score_spread":0.2328621988426043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}