{"id":"W2979902190","doi":"10.1182/blood.v114.22.3578.3578","title":"Genetically-Engineered Endothelial Cells Implanted Into the Omentum of Hemophilia A Dogs Provides Long-Term Circulating FVIII Resulting From Sustained FVIII Expression and Persistent Cell Viability.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Medicine; Genetic enhancement; Cryoprecipitate; Immunology; Andrology; Viral vector; Transgene; Ex vivo; In vivo; Recombinant DNA; Biology; Gene; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638911,0.0001767601,0.0001616293,0.0001734547,0.00009567038,0.0002444383,0.0001205724,0.0003636093,0.001502255],"category_scores_gemma":[0.0001439644,0.0001315625,0.0001488076,0.00007851976,0.0001645968,0.0002294288,0.00009079685,0.0004489952,0.0003920812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001532764,"about_ca_system_score_gemma":0.00009310313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002725051,"about_ca_topic_score_gemma":0.0003845717,"domain_scores_codex":[0.9999213,0.00001380815,0.000006570999,0.00001745904,0.00002120117,0.00001963572],"domain_scores_gemma":[0.9998772,0.00002577903,0.00003560604,0.00001600952,0.00001240875,0.00003300371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002792682,0.0001136291,0.0003566171,0.00002183223,0.000004498208,0.0001534348,0.00002057794,0.00005002769,0.9959012,0.00009521087,0.00009081611,0.002912987],"study_design_scores_gemma":[0.0001263795,0.007261074,0.01566831,0.00001843625,0.00004666279,0.002252615,0.000112995,0.002376073,0.9650139,0.00008639905,0.007024123,0.00001304375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972395,0.0004810867,0.001192964,0.00008438435,0.00003866858,0.00002423241,0.00007753607,0.00004276493,0.0008190051],"genre_scores_gemma":[0.9924844,0.000453515,0.00380557,0.00003800803,0.00001371238,0.000019664,0.0001771545,0.00001425004,0.002993625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001502255,"threshold_uncertainty_score":0.005025506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01197032740874122,"score_gpt":0.2520550719158978,"score_spread":0.2400847445071566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}