{"id":"W2979913180","doi":"10.1016/j.cjca.2019.07.213","title":"MISOPROSTOL ATTENUATES CARDIOMYOCYTE PROLIFERATION IN THE NEONATAL HEART THROUGH A BNIP3-DELTA-EXON3/MEF2-DEPENDENT SIGNALLING PATHWAY","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Research Manitoba","funders":"","keywords":"Hypoxia (environmental); Medicine; Myocardin; Gene isoform; Heart development; Endocrinology; Misoprostol; Internal medicine; Cell biology; Andrology; Biology; Gene expression; Pregnancy; Chemistry; Embryonic stem cell; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011356,0.000250605,0.0002855324,0.0001041541,0.0001214487,0.0001949915,0.0001948393,0.0003004797,0.001586171],"category_scores_gemma":[0.0001339581,0.0001154636,0.0002164392,0.00006333813,0.0002650596,0.000216763,0.0001557995,0.001056286,0.000182252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001888212,"about_ca_system_score_gemma":0.0004155534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007141638,"about_ca_topic_score_gemma":0.001415465,"domain_scores_codex":[0.9998903,0.00001802538,0.00001095561,0.00001813697,0.00002662469,0.00003595919],"domain_scores_gemma":[0.99991,0.00001510112,0.00002310342,0.000008204182,0.000009729124,0.00003383024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001995434,0.0001260722,0.0005843428,0.000112899,0.00001330985,0.0001766702,0.0000331853,0.00009536632,0.9923058,0.0001832629,0.0001602355,0.004213281],"study_design_scores_gemma":[0.0002530531,0.002526385,0.0323755,0.00004749242,0.0001029019,0.0003331103,0.000282495,0.001410498,0.9573445,0.0002403153,0.005067299,0.00001644793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914672,0.003671771,0.001739437,0.0004204641,0.0002313418,0.00002529679,0.0003620022,0.00007081392,0.002011595],"genre_scores_gemma":[0.9928019,0.002296052,0.0009636271,0.0001858708,0.00005505748,0.00005961928,0.0002718019,0.00001476163,0.003351402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001586171,"threshold_uncertainty_score":0.005306244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0130543166395699,"score_gpt":0.2436116640801272,"score_spread":0.2305573474405573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}