{"id":"W2979914430","doi":"10.1093/infdis/jiz522","title":"Discordance in the Epithelial Cell-Dendritic Cell Major Histocompatibility Complex Class II Immunoproteome: Implications for Chlamydia Vaccine Development","year":2019,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Centre for Disease Control; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Chlamydia trachomatis; Biology; Epitope; Chlamydia; Major histocompatibility complex; MHC class I; MHC class II; Antigen; Immune system; T cell; Immunology; Effector; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005625606,0.0002034002,0.0002159404,0.00025617,0.0002206236,0.0006559513,0.0003752579,0.0004726244,0.0007915436],"category_scores_gemma":[0.0007104513,0.0001640858,0.0001314377,0.0001947591,0.0003746038,0.0005028181,0.0003218229,0.0004098686,0.0002096611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004984834,"about_ca_system_score_gemma":0.0002796702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002152058,"about_ca_topic_score_gemma":0.0001730128,"domain_scores_codex":[0.9997174,0.00005478871,0.00002269367,0.00007085352,0.00006298274,0.00007136662],"domain_scores_gemma":[0.9995537,0.00009802475,0.0001650902,0.00005694502,0.00005627365,0.00007001472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002410864,0.00002069919,0.008694815,0.00008222532,0.000009666688,0.0001563294,0.00007865878,0.0001187396,0.9859102,0.0007577969,0.00007650485,0.003853373],"study_design_scores_gemma":[0.00004875731,0.0005421391,0.2698293,0.00007663106,0.00008483297,0.003906239,0.0005654693,0.003809187,0.7082122,0.002063909,0.01082192,0.00003935059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919166,0.003106091,0.003025854,0.0002946947,0.0000292232,0.00002150405,0.0002367054,0.00004327341,0.001326081],"genre_scores_gemma":[0.9979341,0.0003924793,0.001148292,0.0001043636,0.000009561193,0.00001125584,0.0001311267,0.000006568881,0.0002622617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007915436,"threshold_uncertainty_score":0.00361681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01603836356087822,"score_gpt":0.2827776929014713,"score_spread":0.266739329340593,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}