{"id":"W2979940690","doi":"10.1182/blood.v116.21.1942.1942","title":"Responses and Survival Are Not Affected by Cytogenetics In Patients with Relapsed and Refractory Multiple Myeloma (R/R MM) Treated with Single-Agent Carfilzomib","year":2010,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Carfilzomib; Pomalidomide; Lenalidomide; Multiple myeloma; Bortezomib; Cytogenetics; Proteasome inhibitor; Internal medicine; Fluorescence in situ hybridization; Oncology; Medicine; Biology; Chromosome; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005930252,0.0001833197,0.0004609083,0.0002656557,0.0002036006,0.0002586167,0.0001690653,0.0002858663,0.001061193],"category_scores_gemma":[0.0009348731,0.0001230635,0.000298007,0.0002555095,0.0002194983,0.0002038374,0.0001656161,0.0003422298,0.0001846703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003904896,"about_ca_system_score_gemma":0.0002244074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009315064,"about_ca_topic_score_gemma":0.001421055,"domain_scores_codex":[0.9998232,0.00006003341,0.00001501642,0.00003843809,0.00003082655,0.00003246987],"domain_scores_gemma":[0.9995345,0.000139069,0.0001424801,0.00002643647,0.00002525818,0.000132202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.08582658,0.002283275,0.7833388,0.0001992728,0.0005716345,0.001345948,0.0004173834,0.001921415,0.05141475,0.00007183373,0.001380218,0.07122886],"study_design_scores_gemma":[0.002749573,0.0278669,0.9624259,0.00001181373,0.000268666,0.001664829,0.00009113697,0.001182834,0.002568529,0.00004615823,0.001112771,0.00001098204],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994288,0.0002554563,0.00003043443,0.00002687505,0.000002591502,0.00001106409,0.00007718184,0.000004152677,0.0001635163],"genre_scores_gemma":[0.9995968,0.00005802471,0.0000464556,0.00002649905,0.000008454974,0.00001001829,0.0001814162,0.000001106352,0.00007124438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001061193,"threshold_uncertainty_score":0.003550053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01629366573959535,"score_gpt":0.2407367586772273,"score_spread":0.224443092937632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}