{"id":"W2979946059","doi":"10.1182/blood.v118.21.2174.2174","title":"Notch Signaling Requires Gfi1 for T Cell Development","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Biology; T cell; Notch signaling pathway; Transcription factor; Phenotype; Repressor; T-cell receptor; Negative selection; Cell biology; Thymocyte; Genetics; Cre recombinase; Cancer research; Transgene; Molecular biology; Signal transduction; Gene; Genetically modified mouse","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000627501,0.0003476263,0.0001472471,0.0001562381,0.0001435903,0.0002552621,0.0001898459,0.0002866548,0.001462068],"category_scores_gemma":[0.00006589336,0.0001120841,0.000200396,0.00007916024,0.0001930012,0.0001279597,0.0002621711,0.0005991825,0.000652472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004593722,"about_ca_system_score_gemma":0.0002384723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000688824,"about_ca_topic_score_gemma":0.001080355,"domain_scores_codex":[0.9999031,0.000008914255,0.000007867839,0.00002429064,0.0000241354,0.00003177562],"domain_scores_gemma":[0.9998828,0.00001221372,0.0000306165,0.00001285521,0.00001282998,0.00004860275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003335543,0.000005656513,0.0001201327,0.000008071476,7.686202e-7,0.00002279709,0.000003059146,0.00001696963,0.9994392,0.00004449281,0.00001638178,0.000289269],"study_design_scores_gemma":[0.000009171687,0.00008657858,0.005145879,0.000004939984,0.00000555828,0.0001910679,0.00001739196,0.0004114253,0.9920976,0.00003324441,0.001994943,0.000002061838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944279,0.0007193787,0.001314793,0.00008533448,0.00002041553,0.00001848475,0.0006750404,0.00008142021,0.002657306],"genre_scores_gemma":[0.9929945,0.0002972193,0.001152802,0.00005039156,0.000006349937,0.00002766005,0.001267912,0.00002386206,0.004179249],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001462068,"threshold_uncertainty_score":0.004891098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04272021161839167,"score_gpt":0.221965386934548,"score_spread":0.1792451753161563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}