{"id":"W2980014795","doi":"10.1182/blood.v126.23.2502.2502","title":"Treatment-Related Mortality (TRM) in Children with Down Syndrome (DS) and B-Lymphoblastic Leukemia (B-ALL): An Interim Report from the Children's Oncology Group Trials AALL0932 and AALL1131","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Induction chemotherapy; Interim analysis; Internal medicine; Induction therapy; Interim; Adverse effect; Neutropenia; Oncology; Clinical trial; Overall survival; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00162524,0.0005116112,0.001422932,0.0001854614,0.0001003007,0.000102042,0.0002687756,0.0004126782,0.00005685767],"category_scores_gemma":[0.001021353,0.0003012893,0.00009791242,0.0003433998,0.0005963165,0.0002330723,0.0002307138,0.0004353133,0.00001777383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00136827,"about_ca_system_score_gemma":0.001944784,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01378437,"about_ca_topic_score_gemma":0.001162975,"domain_scores_codex":[0.9958845,0.0007468348,0.00105582,0.001030485,0.0006349931,0.0006473586],"domain_scores_gemma":[0.997063,0.0007528528,0.0004070484,0.0009730902,0.0001064988,0.0006975318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001377197,0.001739529,0.9825785,0.00001385567,0.003607478,0.004958551,0.001404666,0.000008836221,0.001059476,0.00004777231,0.0001534837,0.003050622],"study_design_scores_gemma":[0.04897666,0.005486379,0.908564,0.0001368656,0.002095941,0.03342573,0.000244093,0.0002430778,0.0001958992,0.0002081013,0.00009395239,0.000329283],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958904,0.0009379233,0.00003459612,0.0003955384,0.00007924818,0.002050577,0.0001193497,0.0001139806,0.0003783396],"genre_scores_gemma":[0.9977353,0.0002522716,0.0006021917,0.000191817,0.0001966856,0.0001443447,0.0006926606,0.00007297339,0.0001117692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07401451,"threshold_uncertainty_score":0.9999439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04515832847485156,"score_gpt":0.3296787221108517,"score_spread":0.2845203936360001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}