{"id":"W2980014795","doi":"10.1182/blood.v126.23.2502.2502","title":"Treatment-Related Mortality (TRM) in Children with Down Syndrome (DS) and B-Lymphoblastic Leukemia (B-ALL): An Interim Report from the Children's Oncology Group Trials AALL0932 and AALL1131","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Induction chemotherapy; Interim analysis; Internal medicine; Induction therapy; Interim; Adverse effect; Neutropenia; Oncology; Clinical trial; Overall survival; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009722822,0.0004827945,0.00108089,0.0004208746,0.000379809,0.001087493,0.00060844,0.0006720498,0.001492862],"category_scores_gemma":[0.004886653,0.0002640641,0.001955428,0.0007367058,0.0002919479,0.0005337854,0.0007653721,0.002005303,0.000224182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007385655,"about_ca_system_score_gemma":0.00170482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008146341,"about_ca_topic_score_gemma":0.002674873,"domain_scores_codex":[0.9960189,0.00273754,0.0003162366,0.0002233395,0.000441719,0.0002622604],"domain_scores_gemma":[0.9945394,0.001807746,0.002200984,0.0003281374,0.0002827826,0.0008409222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3469589,0.005119183,0.3804697,0.004393887,0.009577582,0.0003718292,0.0003596053,0.004226318,0.006768902,0.000899315,0.036283,0.2045717],"study_design_scores_gemma":[0.1128108,0.109371,0.7233664,0.001090116,0.01068128,0.001304712,0.000271454,0.002986559,0.006853924,0.0007518961,0.03038695,0.0001249165],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9546719,0.02182919,0.000769868,0.002665081,0.0003754456,0.001289048,0.01340619,0.00008245229,0.004910883],"genre_scores_gemma":[0.9769471,0.006744383,0.001619441,0.001445881,0.0005086722,0.001818674,0.01005804,0.00003339323,0.000824448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009722822,"threshold_uncertainty_score":0.05141985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04515832847485156,"score_gpt":0.3296787221108517,"score_spread":0.2845203936360001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}