{"id":"W2980025644","doi":"10.1182/blood.v120.21.295.295","title":"Large-Scale High Resolution Integration of Copy Number and Gene Expression in DLBCL Reveals Focal and Frequent Deletions in Chromatin Modifying Genes with Outcome Correlation","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Jewish General Hospital; BC Cancer Agency","funders":"","keywords":"Diffuse large B-cell lymphoma; Oncology; SNP array; Population; Lymphoma; Biology; Vincristine; CHOP; CDKN2A; Internal medicine; Cancer research; Cancer; Medicine; Cyclophosphamide; Immunology; Genetics; Single-nucleotide polymorphism; Gene; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592729,0.0001146531,0.0002506782,0.0004276924,0.0001870042,0.0002993314,0.0001463193,0.0001434021,0.0009255418],"category_scores_gemma":[0.0003335693,0.0001151315,0.00009403016,0.0005457025,0.0001600076,0.00004233897,0.000234272,0.0002444119,0.0002371638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002786634,"about_ca_system_score_gemma":0.0001630918,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003914091,"about_ca_topic_score_gemma":0.007548434,"domain_scores_codex":[0.9998293,0.0000149251,0.000008094542,0.00005239237,0.00006418469,0.00003096927],"domain_scores_gemma":[0.9998147,0.00005553164,0.00004023211,0.00002880875,0.00003497603,0.00002583688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008999896,0.00004958256,0.2541003,0.00007588232,0.0001052738,0.0003461884,0.0001442472,0.0007343999,0.7283573,0.00008502803,0.0004412023,0.01466071],"study_design_scores_gemma":[0.00001801087,0.00006527812,0.971541,0.000003396927,0.00003559601,0.0004356021,0.00006857739,0.001434294,0.02535105,0.00006963262,0.0009714385,0.000006105519],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974881,0.0001898687,0.0006995798,0.00002232297,0.000001964289,0.000009334004,0.001191833,0.00002707047,0.000369763],"genre_scores_gemma":[0.9961074,0.00007666748,0.0008743431,0.0000341631,0.000002005725,0.00001637648,0.002477896,0.000008160467,0.0004028571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003914091,"threshold_uncertainty_score":0.007782638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01977334577401488,"score_gpt":0.2749280046682969,"score_spread":0.255154658894282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}