{"id":"W2980052074","doi":"10.5114/fn.2019.88449","title":"Lipopolysaccharide-stimulated, NF-kB-, miRNA-146a- and miRNA-155-mediated molecular-genetic communication between the human gastrointestinal tract microbiome and the brain","year":2019,"lang":"en","type":"review","venue":"Folia Neuropathologica","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institutes of Health; University of California, Irvine; University of Kentucky; University of Toronto; Louisiana State University; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; McLean Hospital; Harvard University; Lomonosov Moscow State University; University of Pennsylvania","keywords":"microRNA; Gastrointestinal tract; Microbiome; Human gastrointestinal tract; Lipopolysaccharide; Biology; Bioinformatics; Computational biology; Medicine; Genetics; Immunology; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009136124,0.0007358873,0.001279343,0.0001129158,0.0005265336,0.0001699505,0.001099172,0.0004439301,0.00001575635],"category_scores_gemma":[0.0003406101,0.0004319894,0.0003898898,0.000188346,0.0009382275,0.000006595753,0.0008315856,0.001005219,0.00005324029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002439606,"about_ca_system_score_gemma":0.0001423986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000401751,"about_ca_topic_score_gemma":0.000006762365,"domain_scores_codex":[0.9953351,0.002018276,0.0008930984,0.000977054,0.000153257,0.0006231837],"domain_scores_gemma":[0.997062,0.000464303,0.0007428161,0.00147689,0.00009023744,0.000163812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003476604,0.0006593798,0.006327548,0.01198741,0.0006185885,0.0008280985,0.0004741043,0.00001270899,0.7869383,0.0006550707,0.008038868,0.1831123],"study_design_scores_gemma":[0.003859429,0.001925339,0.018494,0.003618793,0.002420088,0.0131708,0.00003912885,0.00002274865,0.0005630014,0.0002024202,0.9538481,0.001836171],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1275983,0.8689242,0.00006180753,0.0008667085,0.00009365278,0.002002966,0.000300377,0.00004483806,0.0001071752],"genre_scores_gemma":[0.08023678,0.9163877,0.000390639,0.00118427,0.0001820256,0.00009718509,0.001066535,0.0001299906,0.000324863],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9458092,"threshold_uncertainty_score":0.9998132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343416521326232,"score_gpt":0.3170039560768571,"score_spread":0.2826623039442339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}