{"id":"W2980052074","doi":"10.5114/fn.2019.88449","title":"Lipopolysaccharide-stimulated, NF-kB-, miRNA-146a- and miRNA-155-mediated molecular-genetic communication between the human gastrointestinal tract microbiome and the brain","year":2019,"lang":"en","type":"review","venue":"Folia Neuropathologica","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Child Health and Human Development; National Institutes of Health; University of California, Irvine; University of Kentucky; University of Toronto; Louisiana State University; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Eunice Kennedy Shriver National Institute of Child Health and Human Development; McLean Hospital; Harvard University; Lomonosov Moscow State University; University of Pennsylvania","keywords":"microRNA; Gastrointestinal tract; Microbiome; Human gastrointestinal tract; Lipopolysaccharide; Biology; Bioinformatics; Computational biology; Medicine; Genetics; Immunology; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147937,0.0002786434,0.0002154727,0.0001588577,0.0001336408,0.0003363703,0.0001149425,0.000201905,0.001403172],"category_scores_gemma":[0.0002808299,0.0001534002,0.0003763734,0.00009125708,0.000223046,0.0002177175,0.0002205117,0.0004354,0.0006792607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001733796,"about_ca_system_score_gemma":0.0002766412,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002062204,"about_ca_topic_score_gemma":0.0002539905,"domain_scores_codex":[0.999808,0.00002829845,0.00001608726,0.00008539308,0.00003714572,0.00002505995],"domain_scores_gemma":[0.9999055,0.00001609313,0.00002988742,0.0000128783,0.00001874702,0.00001697845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001248689,0.00001959943,0.0003154175,0.00006052632,0.000008461667,0.00003040524,0.00001944516,0.00005502729,0.9970601,0.0001409416,0.00003394355,0.002131163],"study_design_scores_gemma":[0.00002098685,0.0002522984,0.005766341,0.00001353706,0.00002522088,0.0003247277,0.00003214995,0.001445395,0.9896746,0.000273244,0.002161188,0.00001029312],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.957291,0.006364453,0.03097956,0.0002360828,0.0001411531,0.0001323373,0.001132629,0.0002162114,0.003506505],"genre_scores_gemma":[0.971921,0.001369791,0.0221753,0.0001686927,0.00002772175,0.0001462324,0.0009434029,0.00003299869,0.003214849],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001403172,"threshold_uncertainty_score":0.004694104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0343416521326232,"score_gpt":0.3170039560768571,"score_spread":0.2826623039442339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}