{"id":"W2980125828","doi":"10.1182/blood.v128.22.615.615","title":"Obinutuzumab plus Bendamustine Followed by Obinutuzumab Maintenance Prolongs Overall Survival Compared with Bendamustine Alone in Patients with Rituximab-Refractory Indolent Non-Hodgkin Lymphoma: Updated Results of the GADOLIN Study","year":2016,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"","keywords":"Medicine; Obinutuzumab; Bendamustine; Rituximab; Internal medicine; Neutropenia; Refractory (planetary science); Clinical endpoint; Adverse effect; Surgery; Gastroenterology; Oncology; Clinical trial; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002233046,0.0003837967,0.001199597,0.0002944258,0.0001351714,0.000865172,0.000371344,0.0003418392,0.0008006968],"category_scores_gemma":[0.002128406,0.0001656654,0.001629306,0.0004908857,0.0002205473,0.0004183317,0.0003032899,0.0009626908,0.0001058412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005192994,"about_ca_system_score_gemma":0.0005017866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007447731,"about_ca_topic_score_gemma":0.002301292,"domain_scores_codex":[0.999442,0.0003065972,0.00005903644,0.00007477254,0.00007176631,0.0000457017],"domain_scores_gemma":[0.9982432,0.0005937347,0.0006945356,0.0000901994,0.0001301824,0.0002481372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5523025,0.002453826,0.1263324,0.00353605,0.02294332,0.0001939504,0.0003293468,0.002685562,0.01277621,0.0002193757,0.003801443,0.2724259],"study_design_scores_gemma":[0.1851274,0.1381151,0.6087032,0.00102063,0.0458336,0.0006995747,0.0002723375,0.003212461,0.004714004,0.0006140383,0.0115819,0.0001058027],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.967877,0.02947289,0.0002671848,0.0003187699,0.0001035465,0.0001254556,0.0006801702,0.00002342336,0.001131692],"genre_scores_gemma":[0.9920889,0.005978096,0.0003264575,0.0003305884,0.0001237923,0.0000640151,0.0008439955,0.000007496785,0.0002365497],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002233046,"threshold_uncertainty_score":0.01180959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006972763046238773,"score_gpt":0.212124135404898,"score_spread":0.2051513723586592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}