{"id":"W2980126649","doi":"10.1016/j.jhep.2019.09.029","title":"The Candida albicans exotoxin candidalysin promotes alcohol-associated liver disease","year":2019,"lang":"en","type":"article","venue":"Journal of Hepatology","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":228,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Tongji Medical College, Huazhong University of Science and Technology; Huazhong University of Science and Technology; National Institutes of Health; Life Sciences Research Foundation; National Institute on Alcohol Abuse and Alcoholism; Cell Science Research Foundation; Wuhan Union Hospital; Deutsche Forschungsgemeinschaft; Biomedical Laboratory Research and Development, VA Office of Research and Development; Office of Research and Development; U.S. Department of Veterans Affairs","keywords":"Alcoholic liver disease; Alcoholic hepatitis; Candida albicans; Liver disease; Immunology; Liver injury; Medicine; Internal medicine; Biology; Gastroenterology; Microbiology; Cirrhosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000201198,0.0002560494,0.0002213959,0.0004057053,0.0001840833,0.0004071861,0.00009657764,0.0002519526,0.002375325],"category_scores_gemma":[0.0004291563,0.0001449747,0.0002762364,0.0002287486,0.000206913,0.0002046585,0.0004005784,0.000535428,0.0002000255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001738476,"about_ca_system_score_gemma":0.0002159739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008823058,"about_ca_topic_score_gemma":0.0009057675,"domain_scores_codex":[0.9998566,0.00005911633,0.000008503505,0.00001221011,0.0000254701,0.00003810265],"domain_scores_gemma":[0.9995002,0.00008589269,0.0001608661,0.00003952697,0.0000515463,0.0001619666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03739879,0.00135791,0.2430461,0.0002677378,0.0003357804,0.00191003,0.0001618079,0.0003307966,0.695154,0.000448406,0.0005549917,0.01903355],"study_design_scores_gemma":[0.0001243536,0.001641814,0.9210822,0.0000323448,0.0001881367,0.0009678385,0.0002452488,0.001059622,0.07309582,0.0003217857,0.001226405,0.00001440294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979115,0.001127804,0.0001646196,0.00008740512,0.00001924101,0.000005588347,0.00007797503,0.00001514986,0.0005905841],"genre_scores_gemma":[0.9987437,0.0004184355,0.0001065083,0.00002191284,0.00001595981,0.000002509112,0.00006497435,0.000003084546,0.0006229017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002375325,"threshold_uncertainty_score":0.007946312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04603628753030903,"score_gpt":0.3380413731552744,"score_spread":0.2920050856249654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}