{"id":"W2980137220","doi":"10.1182/blood.v110.11.3601.3601","title":"A Phase II Trial of Myeloma Induction Therapy with Cyclophosphamide, Bortezomib, and Dexamethasone (Cybor-D): Improved Response over Historical Lenalidomide-Dexamethasone Controls.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Dexamethasone; Medicine; Multiple myeloma; Bortezomib; Internal medicine; Prednisone; Cyclophosphamide; Gastroenterology; Phases of clinical research; Surgery; Toxicity; Oncology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00172631,0.001201359,0.001566287,0.0003569014,0.0003036179,0.0007506082,0.0007537651,0.0009034232,0.002600658],"category_scores_gemma":[0.0006813185,0.0003613066,0.0006035943,0.0003594452,0.0008804414,0.0004389533,0.0003726727,0.002799706,0.0005367005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006572517,"about_ca_system_score_gemma":0.0009396605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004359423,"about_ca_topic_score_gemma":0.0009900847,"domain_scores_codex":[0.9994729,0.0002910486,0.00002610654,0.00007665481,0.000036162,0.00009708604],"domain_scores_gemma":[0.9993792,0.0001191653,0.00009450495,0.00005388402,0.00002696392,0.0003263527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8430386,0.0583262,0.004000262,0.0005008064,0.0007186559,0.0002535112,0.0001416926,0.0008937051,0.0417916,0.0003040275,0.002203591,0.0478274],"study_design_scores_gemma":[0.671068,0.3140031,0.006638348,0.00002375226,0.0002953828,0.0002219566,0.00002570459,0.0006277089,0.005431347,0.0001120421,0.00153755,0.00001517252],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941981,0.001946454,0.0003413867,0.0003381635,0.0001540141,0.001179051,0.0003847468,0.00006354425,0.001394462],"genre_scores_gemma":[0.9946803,0.0009118671,0.0009280833,0.0004063823,0.0001648257,0.0008316862,0.0009743405,0.00001193131,0.00109054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002600658,"threshold_uncertainty_score":0.009129703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02577585684191883,"score_gpt":0.3137336558421229,"score_spread":0.2879577990002041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}