{"id":"W2980161083","doi":"10.1128/iai.00678-19","title":"Early Growth Response 1 Deficiency Protects the Host against Pseudomonas aeruginosa Lung Infection","year":2019,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Cystic Fibrosis Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; CXCL2; CXCL1; Proinflammatory cytokine; Pseudomonas aeruginosa; Chemokine; Microbiology; Immune system; Immunology; Tumor necrosis factor alpha; Inflammation; Bacteria; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002422904,0.0006427112,0.0006333506,0.0005399447,0.0002030117,0.0003440212,0.0003778893,0.0005776255,0.001376894],"category_scores_gemma":[0.0001821219,0.0002092716,0.0002852774,0.0001601762,0.0003291062,0.0002948295,0.0002299163,0.001311956,0.0003567179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000216682,"about_ca_system_score_gemma":0.0002092489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003733172,"about_ca_topic_score_gemma":0.0004895507,"domain_scores_codex":[0.9998029,0.00003627453,0.00001835142,0.00003345861,0.00003059529,0.00007840674],"domain_scores_gemma":[0.9997032,0.00003570185,0.0000641976,0.00003357123,0.0000199021,0.0001433689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001337316,0.0003063624,0.0003938249,0.00004716658,0.00001407385,0.000101758,0.00001667718,0.00007634041,0.995214,0.00005953494,0.00009333515,0.002339585],"study_design_scores_gemma":[0.0004806583,0.01055075,0.03357055,0.0000675871,0.0001231675,0.001080139,0.0001779815,0.001948014,0.9483346,0.0003497224,0.003271671,0.00004503134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968944,0.001367132,0.000623406,0.0001434408,0.00004240179,0.00001652155,0.0003055728,0.0001072299,0.0004999331],"genre_scores_gemma":[0.9955456,0.00084733,0.0006715982,0.000140474,0.00002043105,0.00003389196,0.0005402061,0.00002810873,0.002172316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001376894,"threshold_uncertainty_score":0.004606187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006958337140128836,"score_gpt":0.2211975115258504,"score_spread":0.2142391743857216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}