{"id":"W2980171540","doi":"10.1182/blood.v122.21.6.6","title":"Head-To-Head Comparison Of Obinutuzumab (GA101) Plus Chlorambucil (Clb) Versus Rituximab Plus Clb In Patients With Chronic Lymphocytic Leukemia (CLL) and Co-Existing Medical Conditions (Comorbidities): Final Stage 2 Results Of The CLL11 Trial","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Internal medicine; Clinical endpoint; Interim analysis; Obinutuzumab; Rituximab; Chlorambucil; Chronic lymphocytic leukemia; Surgery; Oncology; Gastroenterology; Randomized controlled trial; Chemotherapy; Leukemia; Cyclophosphamide; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002246754,0.001511413,0.002913867,0.0003419317,0.0003221474,0.001551443,0.0008525708,0.001222144,0.003709356],"category_scores_gemma":[0.001512854,0.0004431597,0.003227952,0.0003996316,0.0006937456,0.0007077364,0.0004791711,0.002244324,0.0007199328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001007715,"about_ca_system_score_gemma":0.001271427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351826,"about_ca_topic_score_gemma":0.003551181,"domain_scores_codex":[0.9988315,0.0007546051,0.00005490233,0.0001408966,0.00006447266,0.000153718],"domain_scores_gemma":[0.9988901,0.0003017693,0.0002629103,0.00009609455,0.00008468507,0.0003644579],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9820624,0.001929731,0.0009862271,0.0003303439,0.002215673,0.00002067296,0.00002985234,0.0003867327,0.001688884,0.00004881184,0.0006000868,0.0097006],"study_design_scores_gemma":[0.8492522,0.1384073,0.006059008,0.00006368926,0.003486444,0.00004731291,0.00003593868,0.0005822756,0.0007113186,0.0002000078,0.001122175,0.0000322587],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851261,0.007299359,0.0004823758,0.0006171343,0.0004253255,0.00212794,0.001700628,0.00006566567,0.00215539],"genre_scores_gemma":[0.990487,0.001799795,0.0007060614,0.0008931112,0.0003727772,0.001524987,0.001944106,0.00001782787,0.002254343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003709356,"threshold_uncertainty_score":0.01240897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07089950402949753,"score_gpt":0.3653070094932137,"score_spread":0.2944075054637162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}