{"id":"W2980271388","doi":"10.1038/s41467-019-12638-z","title":"Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Health and Medical Research Council; Menzies Foundation; Wellcome Trust; U.S. Department of Defense; Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University; Advanced Research Projects Agency; Harvard University; Defense Advanced Research Projects Agency; Harvard Medical School; National Science Foundation","keywords":"Synthetic biology; Robustness (evolution); Biology; Computational biology; In vivo; Gut flora; Gene expression; Cell biology; Gene; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002625453,0.000154841,0.0002282441,0.0001133026,0.00008682227,0.0002510855,0.0003198424,0.0002850142,0.0004865438],"category_scores_gemma":[0.0003777973,0.0001398173,0.0001695923,0.00009410641,0.0003409807,0.0001850351,0.0003731261,0.0003591176,0.0001410912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002322415,"about_ca_system_score_gemma":0.0001806665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000323185,"about_ca_topic_score_gemma":0.0003967828,"domain_scores_codex":[0.999854,0.00001666932,0.000007446949,0.00005073627,0.00005346103,0.00001770399],"domain_scores_gemma":[0.9998079,0.00005881688,0.00005885525,0.00001968471,0.00002140333,0.0000332741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003523399,0.00000749299,0.0004780252,0.00001828398,0.000003957584,0.00002436719,0.0000172713,0.001828304,0.9960347,0.0003533617,0.00002935074,0.001169598],"study_design_scores_gemma":[0.00004670792,0.0004793794,0.006130145,0.0000135488,0.0000211539,0.0001510473,0.00005892104,0.0942426,0.8931814,0.0007154519,0.004925268,0.00003425388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9502269,0.0002607695,0.04821658,0.0001211212,0.00005270289,0.00001853129,0.0001838417,0.0001622316,0.000757387],"genre_scores_gemma":[0.9792372,0.0002284176,0.01925449,0.0000739439,0.00001485849,0.00004591211,0.0001469622,0.00003676932,0.0009614978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004865438,"threshold_uncertainty_score":0.001684964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009439430101165203,"score_gpt":0.2552685974755103,"score_spread":0.2458291673743451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}