{"id":"W2980302906","doi":"10.1182/blood.v114.22.2606.2606","title":"Secondary Chromosomal Abnormalities Appear to Be Less Prognostic for Children with Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia (ALL) Treated with Intensified Imatinib and Chemotherapy: Results of the Children's Oncology Group (COG) Study AALL0031.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"","keywords":"Medicine; Internal medicine; Etoposide; Chemotherapy; Imatinib; Chemotherapy regimen; Philadelphia chromosome; Acute lymphocytic leukemia; Ifosfamide; Imatinib mesylate; Cohort; Oncology; Gastroenterology; Leukemia; Chromosomal translocation; Lymphoblastic Leukemia; Biology; Myeloid leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007222673,0.0002926484,0.0004283638,0.0004226845,0.0002085869,0.00042412,0.0002576571,0.0003993628,0.0009821057],"category_scores_gemma":[0.001797226,0.0001527995,0.0004397297,0.000603716,0.0002494096,0.0003570484,0.0002555428,0.0006486375,0.0001455779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003811327,"about_ca_system_score_gemma":0.000444535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002489762,"about_ca_topic_score_gemma":0.004578876,"domain_scores_codex":[0.9996873,0.0001178601,0.00002852898,0.0000447037,0.00006446634,0.00005724483],"domain_scores_gemma":[0.9982772,0.0003373241,0.0008665074,0.00004977796,0.00008327675,0.0003859994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001341069,0.00007891009,0.9949881,0.0000121805,0.00006238029,0.0001186112,0.00004205754,0.0000688079,0.0005716692,0.000008182326,0.0001646544,0.002543409],"study_design_scores_gemma":[0.00008057847,0.0005569125,0.9983936,0.000003788229,0.00005027055,0.0004500848,0.00003995499,0.00006763126,0.00008312894,0.000007492379,0.0002642072,0.000002301976],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992303,0.0002925657,0.00002039519,0.00005397088,0.000003065498,0.000007669049,0.0002015947,0.000002322699,0.0001880455],"genre_scores_gemma":[0.9987244,0.0001533909,0.00009094719,0.00005238785,0.00001231233,0.000009367398,0.0008628442,0.000002336765,0.00009200432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002489762,"threshold_uncertainty_score":0.004950523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01231009131436215,"score_gpt":0.2485212168773294,"score_spread":0.2362111255629672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}