{"id":"W2980316438","doi":"10.1182/blood.v120.21.56.56","title":"A Phase I Study of the Anti-CD79b Antibody-Drug Conjugate (ADC) DCDS4501A Targeting CD79b in Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; BC Cancer Agency","funders":"","keywords":"Medicine; Tolerability; Internal medicine; Rituximab; Lymphoma; Oncology; Follicular lymphoma; Diffuse large B-cell lymphoma; Radioimmunotherapy; Antibody-drug conjugate; Gastroenterology; Adverse effect; Antibody; Immunology; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008631813,0.0009429289,0.001125529,0.000283153,0.0003064087,0.000625518,0.0005795098,0.0007318691,0.002220189],"category_scores_gemma":[0.000475164,0.0003547648,0.0007051297,0.0002635319,0.0005287419,0.0004332093,0.0002498814,0.001674814,0.0006709107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005710816,"about_ca_system_score_gemma":0.001042466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001343985,"about_ca_topic_score_gemma":0.001953984,"domain_scores_codex":[0.9997786,0.00008891628,0.00001307006,0.00003986914,0.00002645205,0.00005308628],"domain_scores_gemma":[0.9996753,0.00005948737,0.00005567554,0.00003448826,0.00002585277,0.0001492285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2361334,0.1384449,0.02003464,0.001501208,0.001424789,0.001592277,0.001137566,0.007103409,0.3703112,0.0005943161,0.006106811,0.2156154],"study_design_scores_gemma":[0.2018467,0.7323032,0.02811431,0.00004551962,0.0005384759,0.001205814,0.0001275099,0.002452354,0.02817009,0.0002006549,0.004961366,0.0000338844],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954276,0.0007437001,0.0005651575,0.000145599,0.00002827315,0.001577957,0.0004890784,0.00006091161,0.0009617642],"genre_scores_gemma":[0.9925064,0.001216504,0.00135148,0.0003180921,0.00006327378,0.001246575,0.00161663,0.00002289578,0.001658089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002220189,"threshold_uncertainty_score":0.007427275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02312562710148004,"score_gpt":0.3331881194887565,"score_spread":0.3100624923872765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}