{"id":"W2980328779","doi":"10.1126/sciadv.aaw1644","title":"DNA methylation reprogramming, TE derepression, and postzygotic isolation of nascent animal species","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Derepression; Reprogramming; DNA methylation; Biology; Isolation (microbiology); Methylation; Genetics; DNA; Gene; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002777472,0.00006574266,0.00007239503,0.00004471472,0.00008461551,0.00002039881,0.00009413778,0.00003256365,0.000008126021],"category_scores_gemma":[0.00008645719,0.00005326101,0.00002159122,0.0001609904,0.0002751501,0.00002358777,0.00007715237,0.00002737876,0.000002362287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005988473,"about_ca_system_score_gemma":0.00003943452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003970303,"about_ca_topic_score_gemma":0.000004431696,"domain_scores_codex":[0.9991633,0.00001337399,0.0001332132,0.0003954551,0.0001687946,0.0001258769],"domain_scores_gemma":[0.999504,0.000004092514,0.0001111306,0.0002123814,0.0001339117,0.00003446508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003429968,0.00001405791,0.02994159,0.00001280097,0.000002290625,5.87334e-8,0.00005696871,0.00006807251,0.9562273,0.0001382965,0.000004912072,0.01349935],"study_design_scores_gemma":[0.00009704013,0.0003906048,0.1018849,0.00001229133,0.000004499575,0.00000429588,0.0002880262,0.0001009604,0.8902795,0.0001442839,0.006718262,0.00007538718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957812,0.00273568,0.0007103477,0.00008277893,0.0001559311,0.0001386694,0.000001048746,0.000005468746,0.0003888838],"genre_scores_gemma":[0.997104,0.0002536452,0.002159199,0.00001504343,0.00006561376,0.000002058458,0.00000487668,0.0000042486,0.0003912531],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07194328,"threshold_uncertainty_score":0.2171921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008146836384972054,"score_gpt":0.2690044790657639,"score_spread":0.2608576426807919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}