{"id":"W2980377597","doi":"10.1016/j.chembiol.2019.09.015","title":"Membrane-Active Rhamnolipids Overcome Aminoglycoside Resistance","year":2019,"lang":"en","type":"letter","venue":"Cell chemical biology","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Aminoglycoside; Chemistry; Biology; Antibiotics; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005281342,0.0003990621,0.0004467747,0.0001886668,0.0005054467,0.001025861,0.00044472,0.003881432,0.002352982],"category_scores_gemma":[0.001087905,0.0002456281,0.0002389041,0.0001499309,0.0006889307,0.0007956359,0.0007606663,0.003324819,0.001343662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001138927,"about_ca_system_score_gemma":0.0004279212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007239732,"about_ca_topic_score_gemma":0.000956144,"domain_scores_codex":[0.9996868,0.000053788,0.00002617586,0.00002920459,0.0001189527,0.00008501247],"domain_scores_gemma":[0.999739,0.0001167113,0.00002898867,0.00002350538,0.00004793649,0.00004388135],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002380872,0.0003960938,0.001053883,0.0009062887,0.0001143367,0.01178305,0.0004238175,0.001908466,0.5600272,0.08697245,0.1740383,0.1599952],"study_design_scores_gemma":[0.0004217943,0.0004827821,0.000715262,0.00004798885,0.00003864715,0.002126258,0.0001242056,0.003732926,0.4027696,0.01539347,0.5740908,0.00005631623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.2500909,0.04050509,0.02334163,0.4934861,0.055399,0.0004369949,0.0006771686,0.001194679,0.1348684],"genre_scores_gemma":[0.8070806,0.01790881,0.007149532,0.06371395,0.008079145,0.0002452132,0.0002135278,0.0001855061,0.0954236],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.003881432,"threshold_uncertainty_score":0.008263528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01318910571685287,"score_gpt":0.2179652488939394,"score_spread":0.2047761431770865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}