{"id":"W2980405084","doi":"10.1182/blood-2018-99-114907","title":"New Blood Based M-Protein Quantification Method 3,000 Times More Sensitive Than Standard SPEP","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Polyclonal antibodies; Protein sequencing; Peptide sequence; Biology; Antibody; Molecular biology; Immunology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00215365,0.001211601,0.0006932261,0.001715901,0.000377785,0.001177775,0.001028841,0.001501417,0.003166844],"category_scores_gemma":[0.002098651,0.0006269189,0.0005733786,0.0005804189,0.0004947452,0.0009687002,0.000811758,0.001511131,0.002720857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004965928,"about_ca_system_score_gemma":0.0005174764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004956663,"about_ca_topic_score_gemma":0.0008206094,"domain_scores_codex":[0.9967349,0.0005644652,0.000139524,0.0009998317,0.001444169,0.0001171328],"domain_scores_gemma":[0.9985896,0.0004328389,0.0002133803,0.0001211255,0.0005612003,0.00008200568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001423589,0.0000559007,0.001341284,0.000239666,0.00004441641,0.00007282737,0.00005493394,0.0001746516,0.9666785,0.0002898294,0.001233142,0.02967256],"study_design_scores_gemma":[0.00001919575,0.0003614506,0.00416816,0.00005665079,0.00009331998,0.001308113,0.00004731581,0.009493105,0.9674094,0.0004170808,0.01657513,0.00005112826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.22604,0.02869599,0.7195306,0.001869636,0.00151395,0.000801,0.002057976,0.006110598,0.01338029],"genre_scores_gemma":[0.337891,0.006168996,0.6304994,0.002189764,0.000568046,0.0006973537,0.002031192,0.0004437405,0.01951056],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003166844,"threshold_uncertainty_score":0.01138973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03101908213188804,"score_gpt":0.3459789096556098,"score_spread":0.3149598275237218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}