{"id":"W2980433968","doi":"10.1016/j.celrep.2019.09.010","title":"Polymorphic Immune Mechanisms Regulate Commensal Repertoire","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; University of Toronto; University of Southern California; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Immune system; Repertoire; Commensalism; Biology; Immune escape; Genetics; Computational biology; Immunology; Cell biology; Evolutionary biology; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002914249,0.0001959367,0.0002847622,0.00009738975,0.0001582721,0.00002172643,0.00009940578,0.0002642209,0.01114288],"category_scores_gemma":[0.00002800941,0.0001776577,0.0001699896,0.00009815624,0.00005001123,0.0001389072,0.0000815,0.0003389106,0.004289181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005813697,"about_ca_system_score_gemma":0.00003860235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001275176,"about_ca_topic_score_gemma":0.000001291554,"domain_scores_codex":[0.9985902,0.00009749312,0.0005312927,0.0004070834,0.00004596306,0.0003279984],"domain_scores_gemma":[0.9987444,0.00003945799,0.0003465949,0.0007703775,0.00007685641,0.00002227697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008652539,0.00009267662,0.0006633702,0.00001385239,0.00004793933,0.00006504545,0.00009163501,0.000006168575,0.9834425,0.0002291698,0.0145701,0.0006909833],"study_design_scores_gemma":[0.0005463426,0.0001857236,0.001923412,0.00002809387,0.00002790293,0.0016267,0.0001785849,0.00001265271,0.8050973,0.0003463396,0.1897887,0.0002381472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9033377,0.002466105,0.0004479295,0.000298963,0.02908458,0.0004268249,7.96077e-7,0.0002859253,0.0636512],"genre_scores_gemma":[0.7545573,0.00002065968,0.00003042621,0.0003213894,0.00001890033,0.000008989017,0.000136535,0.00002416012,0.2448817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1812305,"threshold_uncertainty_score":0.9964861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006095418434938091,"score_gpt":0.1944364907814348,"score_spread":0.1883410723464967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}