{"id":"W2980433968","doi":"10.1016/j.celrep.2019.09.010","title":"Polymorphic Immune Mechanisms Regulate Commensal Repertoire","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health; University of Toronto; University of Southern California; National Institute of Diabetes and Digestive and Kidney Diseases; U.S. Department of Defense","keywords":"Immune system; Repertoire; Commensalism; Biology; Immune escape; Genetics; Computational biology; Immunology; Cell biology; Evolutionary biology; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003017675,0.0002266592,0.0001982984,0.0004526885,0.0001508077,0.0004950478,0.0002310998,0.0002518671,0.0008785274],"category_scores_gemma":[0.0002794914,0.0001139111,0.0002052988,0.0001810117,0.0003814577,0.0002803564,0.0004212738,0.0003797882,0.0001755654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001370033,"about_ca_system_score_gemma":0.0001183251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007998741,"about_ca_topic_score_gemma":0.0001426881,"domain_scores_codex":[0.9996709,0.00007303842,0.00002200509,0.00008211985,0.00006936718,0.00008256487],"domain_scores_gemma":[0.999617,0.00005693559,0.0001253377,0.00007653561,0.00004242957,0.00008178179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001870261,0.00002832254,0.006979322,0.00002638242,0.000008779647,0.00006256584,0.00004064409,0.00006988783,0.9876145,0.0003981747,0.00002015216,0.004564203],"study_design_scores_gemma":[0.00005782151,0.001039378,0.3634314,0.00004150916,0.0001049398,0.001609117,0.0003678562,0.002158646,0.6258923,0.001638149,0.003634747,0.00002424526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964553,0.0007642604,0.001926702,0.00002788436,0.000005675224,0.000006291193,0.00007005777,0.00002019737,0.0007235561],"genre_scores_gemma":[0.9975693,0.0003668144,0.001597083,0.00002785567,0.000007283668,0.00001477148,0.00006983128,0.000007598342,0.0003394702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008785274,"threshold_uncertainty_score":0.002938926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006095418434938091,"score_gpt":0.1944364907814348,"score_spread":0.1883410723464967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}