{"id":"W2980456636","doi":"10.1016/j.jalz.2019.06.4850","title":"O5‐03‐05: RETINAL NERVE FIBER LAYER THINNING IN PRE‐CLINICAL ALZHEIMER'S DISEASE PREDICTS CSF AMYLOID/TAU CLASSIFICATION","year":2019,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Retinal Imaging and Analysis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Prism Eye Institute","funders":"","keywords":"Nerve fiber layer; Retinal; Ophthalmology; Medicine; Logistic regression; Inner plexiform layer; Cerebrospinal fluid; Ganglion; Pathology; Internal medicine; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006323327,0.000397045,0.0002068333,0.0004669689,0.0003222272,0.0005640408,0.000391542,0.0005233854,0.005344721],"category_scores_gemma":[0.002104761,0.0001506506,0.0003322189,0.0002617654,0.0002602433,0.0003780024,0.000419173,0.0004310275,0.0007889415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002086552,"about_ca_system_score_gemma":0.0002564652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002481187,"about_ca_topic_score_gemma":0.002445287,"domain_scores_codex":[0.9998013,0.0000375159,0.00002603853,0.00005604505,0.00004811402,0.00003094694],"domain_scores_gemma":[0.998536,0.0002652601,0.0006261652,0.0001069723,0.0002265852,0.0002390536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009092932,0.00009910626,0.994017,0.00001328437,0.00005376293,0.0001194031,0.00004301338,0.0000690504,0.001510802,0.00002987194,0.0002680259,0.002867346],"study_design_scores_gemma":[0.00001777577,0.0002539626,0.9981958,0.000006217678,0.00003386019,0.0004681452,0.00005450997,0.0003824299,0.0003644301,0.00006616289,0.0001532732,0.000003354746],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987558,0.00008921558,0.0001072398,0.00004114762,0.00001174258,0.000006746929,0.0002191563,0.00000834036,0.0007605984],"genre_scores_gemma":[0.9993935,0.00001669189,0.0001090925,0.00001808141,0.000007789382,0.000003452406,0.0001960836,0.000002197976,0.0002531455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005344721,"threshold_uncertainty_score":0.01787984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05127254335878009,"score_gpt":0.3398522656463016,"score_spread":0.2885797222875215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}