{"id":"W2980610937","doi":"10.3390/molecules24203744","title":"Biodegradable Polymers for Gene Delivery","year":2019,"lang":"en","type":"review","venue":"Molecules","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene delivery; Biodegradable polymer; Polymer; Nanotechnology; Genetic enhancement; Chemistry; Gene; Materials science; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008545945,0.0004382799,0.0007945616,0.0001091473,0.00006338405,0.00004534949,0.0004762586,0.0004910276,0.00003448501],"category_scores_gemma":[0.00002696638,0.0003737977,0.0008167388,0.00008624137,0.00005036376,0.000002581701,0.0001532254,0.0001105548,0.0001717915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002287611,"about_ca_system_score_gemma":0.0002989008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002199757,"about_ca_topic_score_gemma":0.000008045113,"domain_scores_codex":[0.9984219,0.00005513655,0.0003618568,0.0006637916,0.0001086104,0.0003887164],"domain_scores_gemma":[0.999003,0.00002197448,0.0001901098,0.0006253198,0.00008049822,0.00007908101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003265506,0.00004277746,0.00000122749,0.003535416,0.0004821604,0.000005612338,0.000004613514,0.000002883767,0.00662826,0.00002557027,0.0168176,0.9724212],"study_design_scores_gemma":[0.0001666145,0.0002716318,3.02854e-7,0.0007250866,0.0004088332,0.00002394147,0.000007739862,0.000005013173,0.007159559,0.000006902187,0.9907622,0.0004621801],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002011383,0.9965494,0.0009874122,0.000009688319,0.0004270839,0.0006713109,0.0004014504,0.00001566137,0.0007368973],"genre_scores_gemma":[0.00002172424,0.9886794,0.0008269355,0.0001880651,0.0003237622,0.0001844917,0.002193511,0.00008930034,0.007492818],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9739446,"threshold_uncertainty_score":0.9998714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04686001067707513,"score_gpt":0.3091615932572077,"score_spread":0.2623015825801325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}