{"id":"W2980612044","doi":"10.1016/j.jalz.2019.06.3826","title":"P4‐164: APOA‐I DEFICIENCY INCREASES CORTICAL AMYLOID DEPOSITION, CEREBRAL AMYLOID ANGIOPATHY, CORTICAL AND HIPPOCAMPAL ASTROGLIOSIS AND AMYLOID‐ASSOCIATED ASTROCYTE REACTIVITY IN APP/PS1 MICE","year":2019,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cerebral amyloid angiopathy; Astrogliosis; Neuroinflammation; Senile plaques; Neurodegeneration; Pathology; Medicine; Hippocampal formation; Amyloid (mycology); Endocrinology; Internal medicine; Inflammation; Alzheimer's disease; Dementia; Disease; Central nervous system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002152113,0.001119888,0.0006544973,0.001097215,0.0003621182,0.00060921,0.0005713266,0.001133829,0.003713909],"category_scores_gemma":[0.0001974401,0.0005611904,0.0005722978,0.0004361094,0.0006380314,0.0004495247,0.0003583617,0.00233626,0.00121669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004986625,"about_ca_system_score_gemma":0.0004931575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00153301,"about_ca_topic_score_gemma":0.001384336,"domain_scores_codex":[0.9995942,0.00004414815,0.00006451303,0.00009995205,0.00008532857,0.0001119313],"domain_scores_gemma":[0.9994553,0.00004166039,0.0001817277,0.00003574572,0.00003348575,0.0002521706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001353511,0.0005883839,0.0002600142,0.00009307965,0.00002565008,0.0002216427,0.00005541923,0.00007145946,0.9959503,0.0001396657,0.0001811555,0.001059604],"study_design_scores_gemma":[0.0004426723,0.004796791,0.0191482,0.0000606805,0.0001565383,0.00122869,0.0002682993,0.00139042,0.9684169,0.000385933,0.003661494,0.00004330527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945256,0.0008824453,0.001001203,0.0003716158,0.0001140982,0.00006293831,0.001540807,0.0002199222,0.001281469],"genre_scores_gemma":[0.978552,0.001626762,0.002850778,0.0003767309,0.00007683225,0.0002785347,0.001901016,0.0001657486,0.01417157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003713909,"threshold_uncertainty_score":0.01242423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01452304842329541,"score_gpt":0.265106057599221,"score_spread":0.2505830091759256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}