{"id":"W2980658977","doi":"10.1182/blood.v118.21.437.437","title":"Inactivating Gene Alterations of MHC Class II Transactivator CIITA Are Recurrent in Primary Mediastinal B Cell Lymphoma and Hodgkin Lymphoma","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"CIITA; Biology; Cancer research; Gene; Genetics; Major histocompatibility complex; MHC class II","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001428056,0.0001827391,0.000247347,0.000348535,0.0001602121,0.0002315524,0.0001288264,0.0001921698,0.001671372],"category_scores_gemma":[0.0002268497,0.0001334517,0.0001171677,0.0002609972,0.0002255296,0.00009360199,0.000185024,0.0002574582,0.0003391452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002117178,"about_ca_system_score_gemma":0.0000998383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004304996,"about_ca_topic_score_gemma":0.0005810573,"domain_scores_codex":[0.9998786,0.00001043553,0.00001036067,0.00004293204,0.00003187375,0.00002572425],"domain_scores_gemma":[0.9998728,0.00002998534,0.00003690092,0.00001540748,0.00001674205,0.00002820405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006399999,0.00006225663,0.09926027,0.0001105121,0.00003996614,0.003506183,0.0002001542,0.0001051542,0.8877606,0.00005512366,0.0001512498,0.008108545],"study_design_scores_gemma":[0.00005165844,0.0005450849,0.8102175,0.00001075843,0.00009883509,0.02091878,0.0002469693,0.0005948293,0.1647934,0.0001079112,0.002404768,0.000009498955],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986399,0.0004353974,0.000316193,0.00001169917,0.000002716972,0.00001040484,0.0001737567,0.00001894403,0.0003909665],"genre_scores_gemma":[0.9990633,0.0001445629,0.0002324494,0.00001703848,0.000003908674,0.00000871132,0.0003102259,0.000005703094,0.000214065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001671372,"threshold_uncertainty_score":0.005591273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02199868864907979,"score_gpt":0.2224743652465704,"score_spread":0.2004756765974905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}