{"id":"W2980670703","doi":"10.1177/1753425919878839","title":"IFN- <b>β</b> signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity","year":2019,"lang":"en","type":"article","venue":"Innate Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Cytokine; Macrophage; Context (archaeology); Immunology; Biology; Proinflammatory cytokine; Immune system; Interferon; Interferon type I; Signalling; Interleukin 10; Inflammation; Cell biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003420266,0.0003228238,0.0003514056,0.0002462638,0.0001643755,0.0004117496,0.0001475789,0.000376593,0.001191791],"category_scores_gemma":[0.0001161018,0.0001386307,0.0003393239,0.0001811478,0.0002580276,0.0002144736,0.0001550872,0.0007327705,0.0007363941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002277484,"about_ca_system_score_gemma":0.000243005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003456944,"about_ca_topic_score_gemma":0.0004423892,"domain_scores_codex":[0.9996648,0.00006814337,0.00004085545,0.00004445743,0.00005959304,0.0001221066],"domain_scores_gemma":[0.9998959,0.0000236328,0.00002392613,0.000008180575,0.00001858928,0.00002966491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002912796,0.00004094377,0.0002290729,0.00002993117,0.000002321926,0.00002833929,0.000009091889,0.00002296531,0.9987141,0.00003332396,0.00002877794,0.0005697538],"study_design_scores_gemma":[0.00005315886,0.0006242525,0.01357902,0.00001913593,0.00001533164,0.0001712407,0.00008804852,0.0007024197,0.9830631,0.000115399,0.001559363,0.000009529439],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924092,0.002907223,0.001948833,0.0002065632,0.00007093902,0.0000302205,0.0006401147,0.00005142289,0.001735398],"genre_scores_gemma":[0.9916413,0.001560164,0.003280684,0.0002595399,0.00004018558,0.00007947509,0.0006918883,0.00002201499,0.002424758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001191791,"threshold_uncertainty_score":0.003986955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009302134960859099,"score_gpt":0.2236971903806754,"score_spread":0.2143950554198163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}