{"id":"W2980670703","doi":"10.1177/1753425919878839","title":"IFN- <b>β</b> signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity","year":2019,"lang":"en","type":"article","venue":"Innate Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Cytokine; Macrophage; Context (archaeology); Immunology; Biology; Proinflammatory cytokine; Immune system; Interferon; Interferon type I; Signalling; Interleukin 10; Inflammation; Cell biology; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008083181,0.0002360594,0.0003037891,0.0001950608,0.000487753,0.00004712516,0.0001909143,0.0002819509,0.0003678648],"category_scores_gemma":[0.000295466,0.0002232307,0.00006521992,0.0002765931,0.0001680431,0.0006162875,0.0001353144,0.000633274,0.0003443822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007128661,"about_ca_system_score_gemma":0.00005992898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002782765,"about_ca_topic_score_gemma":0.000007645509,"domain_scores_codex":[0.9984311,0.0004970707,0.0003374977,0.0003267344,0.00005911863,0.0003485036],"domain_scores_gemma":[0.9988738,0.0002088568,0.0002386294,0.0004653788,0.0001936754,0.00001965158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004968654,0.00007408669,0.0009537906,0.00004383082,0.000112452,9.15597e-7,0.000831519,0.0001353278,0.9886455,0.0001350743,0.0001526396,0.008417997],"study_design_scores_gemma":[0.0006346614,0.0001083403,0.03096063,0.0001201282,0.00002266627,0.00004100542,0.0002117059,0.00007344076,0.9617392,0.0002363173,0.005601737,0.0002501545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966083,0.0007286299,0.0002748319,0.0006465936,0.0006908355,0.0004201104,0.000003585707,0.0001469583,0.0004802109],"genre_scores_gemma":[0.9957304,0.0002260438,0.0000532363,0.0000588574,0.00004623425,0.00001692633,0.00007894742,0.00002738104,0.003761978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03000683,"threshold_uncertainty_score":0.9103084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009302134960859099,"score_gpt":0.2236971903806754,"score_spread":0.2143950554198163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}