{"id":"W2980678340","doi":"10.1002/prot.25838","title":"Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment","year":2019,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Protein Structure and Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; H2020 European Institute of Innovation and Technology; Lietuvos Mokslo Taryba; National Research Foundation of Korea; Francis Crick Institute; Medical Research Council Canada; National Natural Science Foundation of China; Wellcome Trust; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Agence Nationale de la Recherche; National Research Foundation; National Science Foundation; Horizon 2020 Framework Programme; Cancer Research UK","keywords":"CASP; Template; Docking (animal); Protein structure prediction; Computer science; Computational biology; Chemistry; Biology; Protein structure; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001076496,0.0001976033,0.0001754751,0.00005266216,0.0001295648,0.00004956979,0.0001047531,0.0001878262,0.00003334631],"category_scores_gemma":[0.00002048378,0.0001295516,0.00004880065,0.00008519452,0.0001490001,0.00002081551,0.0001322061,0.0001413164,0.000001762672],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009879032,"about_ca_system_score_gemma":0.00003220231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000158595,"about_ca_topic_score_gemma":0.00001404323,"domain_scores_codex":[0.99909,0.00003010593,0.0003316809,0.000190495,0.000184516,0.0001732016],"domain_scores_gemma":[0.9993111,0.000006124277,0.0001977799,0.0003417777,0.00008028973,0.00006296231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004214796,0.00002072386,0.002171047,0.0003316058,0.0001111307,1.951809e-7,0.0004851436,0.00005001879,0.9835645,0.001534723,0.0001207694,0.01118864],"study_design_scores_gemma":[0.007902013,0.005347814,0.02712321,0.0002099671,0.0001858508,0.0002935968,0.003468058,0.016428,0.900891,0.005610287,0.03147417,0.001066043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870951,0.0006112881,0.01024312,0.00008639938,0.0001923762,0.001231277,0.0001235799,0.00001720487,0.0003996742],"genre_scores_gemma":[0.9942572,0.00005621506,0.005081356,0.0001721245,0.0001039221,0.00002745206,0.0001464203,0.00001280453,0.0001425803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08267353,"threshold_uncertainty_score":0.5282961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00675560256241768,"score_gpt":0.2063586023320199,"score_spread":0.1996029997696022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}