{"id":"W2980718125","doi":"10.1161/res.125.suppl_1.155","title":"Abstract 155: Lin28 Enhances Cardiac Progenitor Cell Ability to Repair the Heart by Reprogramming Cellular Metabolism","year":2019,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nicolet Chartrand Knoll (Canada)","funders":"","keywords":"LIN28; Glycolysis; Downregulation and upregulation; Progenitor cell; Cardiac function curve; Cell biology; Biology; Stem cell; Internal medicine; Andrology; Endocrinology; Embryonic stem cell; Metabolism; Medicine; Biochemistry; Heart failure; Induced pluripotent stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001595933,0.0003888397,0.0003215147,0.0002781826,0.0001572837,0.0003430549,0.0002748228,0.0004798406,0.005772193],"category_scores_gemma":[0.00009720463,0.0001185995,0.000295743,0.0001569485,0.0002922266,0.0002537346,0.0002857993,0.001079803,0.001108176],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002546177,"about_ca_system_score_gemma":0.0003826215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002795868,"about_ca_topic_score_gemma":0.0003531086,"domain_scores_codex":[0.9998174,0.00002238007,0.00002174897,0.00004397831,0.00006274969,0.00003181134],"domain_scores_gemma":[0.9998801,0.00001706934,0.00003283484,0.00001183341,0.00001507725,0.00004316491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001197289,0.00006664207,0.0001416926,0.00007548225,0.000004164629,0.00005081396,0.00001178171,0.00004297019,0.9973888,0.00008835058,0.000198357,0.001811277],"study_design_scores_gemma":[0.00005004936,0.0006199174,0.003303629,0.00001370734,0.00002728282,0.0002533307,0.00003340951,0.0004970402,0.9898676,0.00006060299,0.00526925,0.000004187999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982853,0.002336946,0.004652778,0.0005157288,0.0001728527,0.0001137903,0.001780328,0.0003852309,0.007189333],"genre_scores_gemma":[0.9768936,0.001241688,0.004675886,0.0003641366,0.00004671037,0.0002040871,0.002145944,0.0001181707,0.01430983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005772193,"threshold_uncertainty_score":0.01930994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02673237372442342,"score_gpt":0.3222352470565149,"score_spread":0.2955028733320914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}