{"id":"W2980722039","doi":"10.1161/res.125.suppl_1.410","title":"Abstract 410: A Novel Combination Therapy Using First Trimester Human Umbilical Cord-Derived Mesenchymal Stromal Cells and Endothelial Progenitor Cells Significantly Improves Angiogenesis and Cardiac Recovery Following Myocardial Infarction","year":2019,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Brandon University; CReATe Fertility Centre; University of Toronto","funders":"","keywords":"Angiogenesis; Medicine; Progenitor cell; Umbilical cord; Paracrine signalling; Mesenchymal stem cell; Vasculogenesis; Myocardial infarction; Umbilical vein; Stromal cell; Andrology; Ejection fraction; Internal medicine; Cell therapy; Cardiology; Stem cell; Pathology; Immunology; Biology; Heart failure; Cell biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000973874,0.0004554598,0.0003988139,0.0003004708,0.0001082642,0.0002062287,0.0002192275,0.0003247258,0.002430457],"category_scores_gemma":[0.00006003545,0.00008987547,0.0002219933,0.0002076121,0.0001402044,0.0001492027,0.0001590394,0.0004708334,0.000370637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145555,"about_ca_system_score_gemma":0.0002884238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004121523,"about_ca_topic_score_gemma":0.000728082,"domain_scores_codex":[0.9999242,0.00001008933,0.000006802076,0.00001335231,0.00002503992,0.00002054081],"domain_scores_gemma":[0.9999688,0.000003743859,0.000008087869,0.000002462306,0.000003418084,0.00001347615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002640263,0.0009258629,0.0007109761,0.0002167973,0.00004426136,0.0001994199,0.0000356042,0.0002007552,0.9632416,0.0001655631,0.0006738937,0.03094504],"study_design_scores_gemma":[0.000798612,0.01178931,0.009999101,0.00003923037,0.0002744108,0.0008005415,0.00005095083,0.001870682,0.9651175,0.00008582948,0.009160794,0.000013092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926828,0.002247709,0.002049074,0.0001710823,0.0001169367,0.0001030893,0.0002705093,0.0001303215,0.002228494],"genre_scores_gemma":[0.9900733,0.002212074,0.002682364,0.00009676381,0.00006607201,0.0001275618,0.0005397188,0.00001579822,0.004186247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002430457,"threshold_uncertainty_score":0.008130729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08067742441442076,"score_gpt":0.3503872127745088,"score_spread":0.2697097883600881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}