{"id":"W2980783706","doi":"10.1002/stem.3097","title":"Epidermal growth factor receptor-extracellular-regulated kinase blockade upregulates TRIM32 signaling cascade and promotes neurogenesis after spinal cord injury","year":2019,"lang":"en","type":"article","venue":"Stem Cells","topic":"Spinal Cord Injury Research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; Youth Innovation Promotion Association of the Chinese Academy of Sciences; Youth Innovation Promotion Association; Chinese Academy of Sciences; Institute of Genetics; National Natural Science Foundation of China","keywords":"Neurogenesis; MAPK/ERK pathway; Biology; Cell biology; Myelin; Neural stem cell; Neuroprotection; Kinase; Spinal cord injury; Neuroscience; Stem cell; Spinal cord; Central nervous system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004243093,0.00052949,0.0007860629,0.0003588048,0.0001227236,0.0001097585,0.0002478234,0.0003208914,0.001373426],"category_scores_gemma":[0.00004802965,0.0004652504,0.0002349235,0.0005368974,0.0001961449,0.0002372555,0.0002101719,0.000581274,0.0005152125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001230685,"about_ca_system_score_gemma":0.0001793984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007466108,"about_ca_topic_score_gemma":0.00000165539,"domain_scores_codex":[0.9963556,0.000273155,0.000697421,0.0009665449,0.0007862239,0.000921039],"domain_scores_gemma":[0.9981351,0.0001574089,0.0001924712,0.0006437511,0.0003049728,0.000566241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01514159,0.0001559219,0.01985193,0.0007185651,0.0001253031,0.0002226728,0.00005701645,9.36789e-7,0.9515948,0.00001010013,0.0001764392,0.01194471],"study_design_scores_gemma":[0.0014348,0.009004705,0.01759458,0.0004191967,0.0001430089,0.0001271574,0.00009568975,0.0002929016,0.968679,0.00001829991,0.001712705,0.0004779855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937198,0.003233532,0.00002267025,0.0005249744,0.000363393,0.001804035,0.000081442,0.0001625686,0.00008765368],"genre_scores_gemma":[0.9935197,0.00008935493,0.0005673982,0.0001341359,0.0002612761,0.00005963364,0.00002092262,0.0001289989,0.005218586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01708415,"threshold_uncertainty_score":0.9997799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02748330353219579,"score_gpt":0.2998919186954417,"score_spread":0.2724086151632459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}