{"id":"W2980807059","doi":"10.3390/toxins11100604","title":"Channel Formation by LktA of Mannheimia (Pasteurella) haemolytica in Lipid Bilayer Membranes and Comparison of Channel Properties with Other RTX-Cytolysins","year":2019,"lang":"en","type":"article","venue":"Toxins","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Microbiology; Cytolysin; Chemistry; Bordetella pertussis; Biology; Biochemistry; Bacteria; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000205115,0.000188613,0.0001764841,0.0001681264,0.000146721,0.0002719982,0.0001677472,0.0003478939,0.0002957126],"category_scores_gemma":[0.0004877574,0.0001037828,0.0002520581,0.0001636537,0.0002347487,0.000576058,0.0001905931,0.000300926,0.0001178751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002297265,"about_ca_system_score_gemma":0.00009298459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004018494,"about_ca_topic_score_gemma":0.0001672147,"domain_scores_codex":[0.9998114,0.00004544403,0.00001476148,0.00004057424,0.0000361721,0.00005182042],"domain_scores_gemma":[0.9996252,0.0001484334,0.0001063738,0.00002004818,0.00006625277,0.00003362237],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001139251,0.00001276834,0.0003630191,0.00003359184,0.000005333967,0.00003733725,0.00004607919,0.0001102505,0.9988757,0.00007456593,0.000009449044,0.0003179167],"study_design_scores_gemma":[0.00002692908,0.0006059892,0.01537441,0.00001706582,0.00003278683,0.0003529562,0.0001861927,0.005210402,0.9771916,0.0001448066,0.000838422,0.00001857241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986501,0.0003476297,0.0007502439,0.00002577953,0.000006323934,0.000006019856,0.00006305077,0.00001217017,0.0001386907],"genre_scores_gemma":[0.9985186,0.0002927689,0.000824036,0.00001296717,0.00000543578,0.00001287948,0.0001250233,0.00000683916,0.0002013887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004018494,"threshold_uncertainty_score":0.001666844,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02687327669319315,"score_gpt":0.2585167100288153,"score_spread":0.2316434333356222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}