{"id":"W2980816248","doi":"10.1056/nejmc1911063","title":"Drug-Induced Liver Injury — Types and Phenotypes","year":2019,"lang":"en","type":"letter","venue":"New England Journal of Medicine","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Phenotype; Liver injury; Drug; MEDLINE; Bioinformatics; Computational biology; Pharmacology; Genetics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001884117,0.0004102376,0.0009237458,0.0004339786,0.0001414545,0.00002025465,0.0003315095,0.001194555,0.001289875],"category_scores_gemma":[0.0003607875,0.0003001355,0.0001231414,0.0001719626,0.0001736608,0.0001604341,0.00006107906,0.006814132,0.0001063109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009135101,"about_ca_system_score_gemma":0.0002961754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001880179,"about_ca_topic_score_gemma":0.00003273656,"domain_scores_codex":[0.9972356,0.0008736991,0.0007313369,0.0002856516,0.000462572,0.0004111584],"domain_scores_gemma":[0.9974167,0.001070031,0.0008203315,0.0002015376,0.0002495938,0.0002417583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005593676,0.00002938468,0.0003162488,0.0002269021,0.0003325152,0.0005408676,0.001215654,0.000006143892,0.00500576,0.00002856693,0.7584544,0.2332842],"study_design_scores_gemma":[0.01183598,0.0008598606,0.0001270618,0.0003443563,0.000621958,0.0008774911,0.00003349885,0.00005742685,0.002872028,0.0008062878,0.981267,0.0002970232],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.160693,0.007336651,0.00006831525,0.8046021,0.01793678,0.0007339314,0.00003778858,0.00005837022,0.008533072],"genre_scores_gemma":[0.2411949,0.005381152,0.000145353,0.6415256,0.09694797,0.00000629337,0.00004567098,0.0001055796,0.0146475],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2329872,"threshold_uncertainty_score":0.9999451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09896719180701125,"score_gpt":0.3861000618657783,"score_spread":0.287132870058767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}