{"id":"W2980832688","doi":"10.1093/nar/gkz882","title":"MIBiG 2.0: a repository for biosynthetic gene clusters of known function","year":2019,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":620,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Center for Complementary and Integrative Health; Novo Nordisk Fonden; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Netherlands eScience Center; Statens Naturvidenskabelige Forskningsrad","keywords":"Biology; Function (biology); Gene; Genetics; Computational biology; Gene cluster","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000989274,0.0001163884,0.0002959475,0.0002732321,0.0001137466,0.0000214889,0.0001644358,0.0001699592,0.0003722845],"category_scores_gemma":[0.0003293291,0.0000857055,0.0001487125,0.0003685184,0.0001768735,0.00006375788,0.00009294322,0.0002983522,0.0001565806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009963498,"about_ca_system_score_gemma":0.0001127657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005638254,"about_ca_topic_score_gemma":0.000001996451,"domain_scores_codex":[0.9983301,0.0001038477,0.0002866107,0.0004091426,0.000476251,0.000394012],"domain_scores_gemma":[0.9985855,0.000189119,0.00006384993,0.0005467547,0.0005021234,0.0001126592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001399896,0.0001294388,0.0008182023,0.0004301391,0.00006734743,0.000003122767,0.00008726014,7.49249e-7,0.9766015,0.0001077549,0.008131132,0.01222345],"study_design_scores_gemma":[0.001229223,0.001747736,0.003896899,0.0002157275,0.00006605635,0.00004386144,0.0002111716,0.000376356,0.92787,0.000114275,0.06409146,0.0001372316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910415,0.000472603,0.00003103866,0.002003467,0.0003731606,0.001199078,0.00001374365,0.00003412887,0.004831288],"genre_scores_gemma":[0.985088,0.00004973555,0.001040049,0.00009750232,0.0003344842,0.000004652871,0.00001296981,0.0000314688,0.01334116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05596033,"threshold_uncertainty_score":0.4076255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03563045710569186,"score_gpt":0.3105331778053209,"score_spread":0.274902720699629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}