{"id":"W2980868249","doi":"10.1002/adfm.201906330","title":"3D Printed Cartilage‐Like Tissue Constructs with Spatially Controlled Mechanical Properties","year":2019,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":159,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Biomedical Imaging and Bioengineering; European Research Council; Qatar National Research Fund; Arthritis Society; Brigham and Women's Hospital; Strong; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Department of Biotechnology, Ministry of Science and Technology, India; Dutch Arthritis Society; Fonds National de la Recherche Luxembourg; Fundação de Amparo à Pesquisa do Estado de São Paulo; National Institutes of Health; National Science Foundation","keywords":"Materials science; Biomaterial; Chondrogenesis; Cartilage; Biomedical engineering; Tissue engineering; Self-healing hydrogels; Extracellular matrix; 3D bioprinting; Nanotechnology; Anatomy; Chemistry; Polymer chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000110642,0.0002571959,0.0007024062,0.00006862527,0.00006852008,0.00003573085,0.00004700156,0.00010333,0.003093286],"category_scores_gemma":[0.00005233414,0.0001700029,0.00005285604,0.00007460208,0.00005892037,0.0001681023,0.00003379954,0.00007638837,0.0004678404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006274212,"about_ca_system_score_gemma":0.0001475599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007013613,"about_ca_topic_score_gemma":0.00001269465,"domain_scores_codex":[0.9985416,0.00005471428,0.0003627946,0.0003859315,0.0003612704,0.000293707],"domain_scores_gemma":[0.9991904,0.00004530175,0.0001400745,0.0002744349,0.0002271224,0.0001226909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01450088,0.0000960202,0.00008460138,0.00006260047,0.00007680983,0.00005016982,0.00002139017,0.00002506849,0.9811699,0.002171236,0.00001604262,0.00172532],"study_design_scores_gemma":[0.02523571,0.004007312,0.000178024,0.0002706714,0.0001670372,0.00026873,0.00006061896,0.0000065453,0.9673303,0.0001525492,0.002112398,0.0002100831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938446,0.0001402436,0.0003657657,0.0001739982,0.001666122,0.002229129,0.00002906778,0.0001663895,0.001384648],"genre_scores_gemma":[0.9870504,0.00001184516,0.004333447,0.0003867015,0.0001758925,0.000268437,0.0001322772,0.00004289814,0.007598099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01383954,"threshold_uncertainty_score":0.997818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007908310278366,"score_gpt":0.216284313068706,"score_spread":0.2062052299659224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}