{"id":"W2980898979","doi":"10.1002/iub.2184","title":"Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche","year":2019,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cambridge Institute for Medical Research, University of Cambridge; Blood Cancer UK; Wellcome Trust; Bloodwise; Kay Kendall Leukaemia Fund; Medical Research Council; British Society for Haematology; Medical Research Council Canada","keywords":"RUNX1; Biology; Cell biology; Haematopoiesis; Embryonic stem cell; Stem cell; Transcription factor; Stromal cell; GATA3; Immunology; Cancer research; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004995362,0.0001193697,0.0001262444,0.00004044029,0.00004721947,0.00003589436,0.0006516571,0.0001411142,0.0001116233],"category_scores_gemma":[0.0000983268,0.00008659991,0.00007011062,0.0002162393,0.00009382807,0.000003522258,0.0001704498,0.0002134857,0.0007268654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001705101,"about_ca_system_score_gemma":0.0002069362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001761724,"about_ca_topic_score_gemma":0.00002458828,"domain_scores_codex":[0.9986524,0.0001224204,0.0001866733,0.00033573,0.0003221423,0.0003806619],"domain_scores_gemma":[0.9989561,0.00006478696,0.00004941527,0.0007301046,0.00004107054,0.0001585356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001007747,0.0006189297,0.01427452,0.0002298269,0.00006384032,0.00002357217,0.0003814295,0.00003323989,0.7633765,0.001999637,0.2159748,0.002922922],"study_design_scores_gemma":[0.001701754,0.0003946218,0.02523632,0.00003005813,0.0000161103,0.00002213877,0.0008597513,0.0002812328,0.1287087,0.0005002003,0.8418069,0.0004422233],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839963,0.001694777,0.0002217498,0.004543659,0.00008551186,0.0006454188,0.00001812665,0.00001414943,0.008780313],"genre_scores_gemma":[0.9950012,0.0001479024,0.00008544642,0.002108602,0.0001295426,0.0001394403,0.0000756935,0.00001871726,0.002293472],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6346679,"threshold_uncertainty_score":0.9342626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01109901285615192,"score_gpt":0.2677751403545858,"score_spread":0.2566761274984339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}