{"id":"W2980920904","doi":"10.1101/809848","title":"Centromere scission drives chromosome shuffling and reproductive isolation","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; North Carolina State University; Canadian Institute for Advanced Research","keywords":"Biology; Centromere; Chromosomal translocation; Genetics; Sexual reproduction; Reproductive isolation; Chromothripsis; Chromosomal rearrangement; Chromosome; Genome; Ploidy; Karyotype; Gene; Genome instability; DNA; DNA damage; Population","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003136478,0.0004343243,0.0002298475,0.0003563134,0.0002107279,0.0004317438,0.000381289,0.0003725326,0.002538806],"category_scores_gemma":[0.0002516578,0.0002001651,0.0002669262,0.000215261,0.0004049186,0.0001988126,0.0006884112,0.0008262903,0.0007143031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003637509,"about_ca_system_score_gemma":0.0002160258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003698542,"about_ca_topic_score_gemma":0.0006826089,"domain_scores_codex":[0.9997872,0.00003350221,0.00001858299,0.00005888317,0.00006250483,0.00003945718],"domain_scores_gemma":[0.9997851,0.00004852909,0.00007009955,0.00004151879,0.00001233587,0.00004242377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004683152,0.0000238105,0.0001489071,0.00004294696,0.000008516447,0.0001146269,0.00001755355,0.0001583973,0.9969892,0.0006856481,0.00009878171,0.0016647],"study_design_scores_gemma":[0.00002594679,0.0001137322,0.00180459,0.00001093151,0.00001059071,0.0004142809,0.00002877268,0.003110949,0.98771,0.0003552896,0.006405926,0.000009099352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9526899,0.001676157,0.03272012,0.0003517522,0.0001592652,0.0001976294,0.0008797015,0.0006660224,0.01065945],"genre_scores_gemma":[0.9871229,0.0004925436,0.00574673,0.00007417444,0.00001114734,0.00005216724,0.0005582655,0.0001001378,0.005841928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002538806,"threshold_uncertainty_score":0.008493125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01471425381701673,"score_gpt":0.2396429422445433,"score_spread":0.2249286884275266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}