{"id":"W2981064702","doi":"10.1200/jco.19.01507","title":"Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Oral health in cancer treatment","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Health Sciences North","funders":"","keywords":"Mucositis; Medicine; Head and neck cancer; Placebo; Cisplatin; Radiation therapy; Oncology; Internal medicine; Randomized controlled trial; Head and neck; Cancer; Surgery; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003688043,0.0002056558,0.003303676,0.000148885,0.00003616248,0.00001010511,0.00009760039,0.0003179889,0.0001616733],"category_scores_gemma":[0.001015924,0.0001457986,0.0003499418,0.0001213644,0.0001542566,0.0000757953,0.00003676587,0.0004600142,0.000003174582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004891673,"about_ca_system_score_gemma":0.00212187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001866823,"about_ca_topic_score_gemma":0.0002015924,"domain_scores_codex":[0.9961782,0.0003940258,0.002459189,0.0003135025,0.000325967,0.0003291332],"domain_scores_gemma":[0.9921312,0.005108126,0.00132142,0.0001768941,0.0003826261,0.0008796841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7403551,0.001380786,0.0004017958,0.0001020974,0.0005091681,0.00004221609,0.0002249453,0.00002043438,0.00005014374,0.00003836209,0.003014981,0.2538599],"study_design_scores_gemma":[0.8469357,0.1188061,0.0005057801,0.0003240964,0.0005638537,0.0001375788,0.00004327783,0.0001594656,0.0001537432,0.00002474359,0.03223331,0.0001123079],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9647899,0.001964597,0.0001854198,0.02101944,0.006322139,0.005529172,0.00004199299,0.000005258792,0.0001420373],"genre_scores_gemma":[0.9780648,0.002130137,0.01398273,0.002797998,0.002465815,0.0002077939,0.000004593201,0.00003318087,0.0003129492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2537476,"threshold_uncertainty_score":0.5945493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2588300535395386,"score_gpt":0.5843787431077885,"score_spread":0.3255486895682498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}