{"id":"W2981064702","doi":"10.1200/jco.19.01507","title":"Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Oral health in cancer treatment","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Health Sciences North","funders":"","keywords":"Mucositis; Medicine; Head and neck cancer; Placebo; Cisplatin; Radiation therapy; Oncology; Internal medicine; Randomized controlled trial; Head and neck; Cancer; Surgery; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001952227,0.002176872,0.003972698,0.0006720508,0.0008014826,0.001040025,0.001240661,0.002334518,0.009027238],"category_scores_gemma":[0.001947294,0.000954402,0.001460759,0.0005852127,0.001792387,0.001005454,0.000486487,0.002637688,0.001473506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009736032,"about_ca_system_score_gemma":0.002163776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351524,"about_ca_topic_score_gemma":0.00273217,"domain_scores_codex":[0.9991616,0.0004399091,0.00005955822,0.0001489087,0.00006287837,0.000127195],"domain_scores_gemma":[0.9989156,0.0002103506,0.0002922307,0.0001149808,0.00008896195,0.0003779976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9741151,0.01187415,0.0002745609,0.0002942383,0.0003397878,0.00001742688,0.00003132018,0.0002036365,0.002804986,0.00006739895,0.0005235909,0.009453861],"study_design_scores_gemma":[0.9476476,0.05104434,0.0005006767,0.00001189752,0.000104377,0.000009702751,0.000007051857,0.0001782101,0.000259049,0.00004471028,0.0001854661,0.000006942707],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821398,0.002464124,0.0007987393,0.0005637982,0.0006863737,0.01023798,0.001024271,0.0002266982,0.001858278],"genre_scores_gemma":[0.9737552,0.002133567,0.00266173,0.001439145,0.0006887739,0.01389734,0.00106142,0.00003696052,0.004325696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009027238,"threshold_uncertainty_score":0.03019911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2588300535395386,"score_gpt":0.5843787431077885,"score_spread":0.3255486895682498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}