{"id":"W2981120128","doi":"10.1182/blood-2018-99-116256","title":"MiR-193a Is a Negative Regulator of Hematopoietic Stem Cells and Promotes Anti-Leukemic Effects in Acute Myeloid Leukemia","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Haematopoiesis; Myeloid; Stem cell; Myeloid leukemia; Biology; Cancer research; Progenitor cell; Hematopoietic stem cell; microRNA; Leukemia; Hematopoietic growth factor; Granulocyte colony-stimulating factor; Immunology; Cell biology; Genetics; Gene; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001876174,0.0002783694,0.0003170838,0.0003585901,0.0002112536,0.0002871942,0.0001518111,0.000175214,0.002252761],"category_scores_gemma":[0.0001850099,0.0001578334,0.0003431644,0.0002219416,0.0002342278,0.000150119,0.0002021657,0.0006947148,0.0008225294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003021038,"about_ca_system_score_gemma":0.0002159799,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005577875,"about_ca_topic_score_gemma":0.0006118699,"domain_scores_codex":[0.9998403,0.00002290302,0.00001917162,0.00002585242,0.00006201189,0.00002985038],"domain_scores_gemma":[0.9999081,0.00001821426,0.00002606769,0.00001150117,0.00001308722,0.00002294366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001618447,0.00003443422,0.0003120775,0.00003369138,0.000005263277,0.00005207197,0.000009279252,0.00003573053,0.9974883,0.00009792589,0.0001399589,0.001629496],"study_design_scores_gemma":[0.00006976107,0.0004861627,0.009420888,0.00001206174,0.00003979227,0.000417446,0.00003533424,0.001343483,0.980131,0.0001542464,0.007882227,0.0000075174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9803329,0.005882571,0.00700939,0.0002936356,0.0001709097,0.0001057502,0.001716295,0.0003782521,0.00411027],"genre_scores_gemma":[0.9937529,0.001180206,0.002418458,0.0001041602,0.00001865757,0.00005812761,0.0008440777,0.00003524492,0.001588271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002252761,"threshold_uncertainty_score":0.007536232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004907692437086848,"score_gpt":0.2181479110652298,"score_spread":0.2132402186281429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}