{"id":"W2981129322","doi":"10.1016/j.ahj.2019.09.011","title":"The effect of low-dose colchicine in patients with stable coronary artery disease: The LoDoCo2 trial rationale, design, and baseline characteristics","year":2019,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Health and Medical Research Council; Hartstichting; ZonMw","keywords":"Medicine; Coronary artery disease; Myocardial infarction; Internal medicine; Clinical endpoint; Colchicine; Adverse effect; Placebo; Stroke (engine); Cardiology; Revascularization; Randomized controlled trial; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005425488,0.00009948743,0.0001688779,0.00002178324,0.0001091944,0.00002629061,0.00008678104,0.000017401,0.00001301903],"category_scores_gemma":[0.0001128238,0.00005190462,0.00004051276,0.00007072245,0.0001722752,0.000007873265,0.00002909159,0.0001236014,0.000002095704],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008367007,"about_ca_system_score_gemma":0.00009996327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005194934,"about_ca_topic_score_gemma":0.00000339677,"domain_scores_codex":[0.9990349,0.0003361311,0.0002205971,0.0001068475,0.000144467,0.0001569982],"domain_scores_gemma":[0.9993889,0.0001648155,0.0001479406,0.0001726765,0.00007979535,0.00004581104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.08518922,0.0001220227,0.8952082,0.00001967318,0.0001075049,0.000004146552,0.00004764302,0.0002334998,0.01116689,0.000002342469,0.0009117283,0.006987068],"study_design_scores_gemma":[0.01627174,0.006781437,0.9705709,0.00004363973,0.00003225065,0.00001530025,0.0000769096,0.0002237306,0.001795587,0.00000428395,0.004051349,0.0001328323],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985435,0.0002822569,0.0001251447,0.000233757,0.00009007118,0.0007075879,0.000008533954,0.000001067869,0.000008050921],"genre_scores_gemma":[0.9993533,0.0001805606,0.00004306159,0.0002022114,0.00007285774,0.00001737423,0.00003832762,0.00001085321,0.0000814602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07536267,"threshold_uncertainty_score":0.2116609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003475652574798154,"score_gpt":0.2142281379448485,"score_spread":0.2107524853700503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}