{"id":"W2981176667","doi":"10.1016/j.beha.2019.101096","title":"Can Ph-like ALL be effectively targeted?","year":2019,"lang":"en","type":"review","venue":"Best Practice & Research Clinical Haematology","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"CANDU Owners Group; Pfizer","keywords":"Lymphoblastic Leukemia; Medicine; Immunotherapy; Oncology; Chemotherapy; Philadelphia chromosome; Cytokine; Cancer research; Clinical trial; Internal medicine; Blinatumomab; Leukemia; Biology; Genetics; Chromosomal translocation; Gene; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.02398529,0.001277152,0.00975291,0.001541137,0.0003569234,0.0002076049,0.002230302,0.004304996,0.0008604378],"category_scores_gemma":[0.1461576,0.0009767863,0.002081408,0.002191058,0.003006486,0.0004384782,0.00280367,0.01599946,0.01472299],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002856358,"about_ca_system_score_gemma":0.02555914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008921294,"about_ca_topic_score_gemma":0.0000990182,"domain_scores_codex":[0.964729,0.02044116,0.003814254,0.003230203,0.004232899,0.003552563],"domain_scores_gemma":[0.8733799,0.1162834,0.00140427,0.00362774,0.003124813,0.002179909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002080669,0.005701002,0.00007587114,0.05661072,0.005440308,0.03303027,0.0001154539,1.677592e-7,0.000001693406,0.00292787,0.1832615,0.7107545],"study_design_scores_gemma":[0.003667264,0.006190029,0.000004987974,0.009563016,0.004637126,0.02251067,0.0001776284,0.00005430404,0.00000159129,0.0001048218,0.952375,0.0007135507],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005396939,0.9576036,0.00004544417,0.01383145,0.001640167,0.008700809,0.0001482415,0.0001849097,0.0177914],"genre_scores_gemma":[0.00004588588,0.9810831,0.001730246,0.002244406,0.001293789,0.001201228,0.0006265985,0.0004431201,0.01133165],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7691135,"threshold_uncertainty_score":0.999998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.346324702314614,"score_gpt":0.5833636105843084,"score_spread":0.2370389082696944,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}